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Technology Process of (+)-YK-4-279

(+)-YK-4-279

Base Information
(+)-YK-4-279

Synonyms:(3R)-4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one;2H-Indol-2-one, 4,7-dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-, (3R)-

Suppliers and Price of (+)-YK-4-279
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Cayman Chemical
  • (+)-YK-4-279 ≥98%
  • 25mg
  • $ 1050.00
  • Cayman Chemical
  • (+)-YK-4-279 ≥98%
  • 10mg
  • $ 480.00
  • Cayman Chemical
  • (+)-YK-4-279 ≥98%
  • 5mg
  • $ 270.00
  • Cayman Chemical
  • (+)-YK-4-279 ≥98%
  • 1mg
  • $ 60.00
Total 2 raw suppliers
Chemical Property of (+)-YK-4-279
Chemical Property:
  • PSA：75.63000 
  • LogP:3.55270 
Purity/Quality:

99% *data from raw suppliers

(+)-YK-4-279 ≥98% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
Technology Process of (+)-YK-4-279

There total 1 articles about (+)-YK-4-279 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4,7-dichloroisatin
18711-13-2

4,7-dichloroisatin

(R)-4,7-dichloro-3-hydroxy-3-[2-oxo-2-(4-methoxyphenyl)ethyl]indolin-2-one
1261038-93-0

(R)-4,7-dichloro-3-hydroxy-3-[2-oxo-2-(4-methoxyphenyl)ethyl]indolin-2-one

Guidance literature:
4,7-dichloroisatin; With N-[3,5-bis(trifluoromethyl)phenyl]-N'-[(9R)-6'-methoxycinchonan-9-yl]thiourea; In tetrahydrofuran; at 5 ℃; for 0.166667h;
1-(4-methoxyphenyl)ethanone; In tetrahydrofuran; at 5 ℃; for 144h; optical yield given as %ee; enantioselective reaction;
DOI:10.1002/anie.201004161
upstream raw materials:

4,7-dichloroisatin

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