5-(benzyloxy)-3-broMo-2-(2,5-diMethyl-1H-pyrrol-1-yl)pyridine

Base Information

Chemical Name:5-(benzyloxy)-3-broMo-2-(2,5-diMethyl-1H-pyrrol-1-yl)pyridine
CAS No.:1262133-29-8
Molecular Formula:C18H17BrN2O
Molecular Weight:357.25
Hs Code.:
Mol file:1262133-29-8.mol

Synonyms:5-(benzyloxy)-3-broMo-2-(2,5-diMethyl-1H-pyrrol-1-yl)pyridine

Suppliers and Price of 5-(benzyloxy)-3-broMo-2-(2,5-diMethyl-1H-pyrrol-1-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-(Benzyloxy)-3-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine 95%
1g
$ 363.00

Total 2 raw suppliers

Chemical Property of 5-(benzyloxy)-3-broMo-2-(2,5-diMethyl-1H-pyrrol-1-yl)pyridine

Chemical Property:

PSA：27.05000
LogP:4.83060

Purity/Quality:

99% ^*data from raw suppliers

5-(Benzyloxy)-3-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(benzyloxy)-3-broMo-2-(2,5-diMethyl-1H-pyrrol-1-yl)pyridine

There total 3 articles about 5-(benzyloxy)-3-broMo-2-(2,5-diMethyl-1H-pyrrol-1-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1210477-73-8
3,5-dibromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine

: 100-51-6,185532-71-2
benzyl alcohol

: 1262133-29-8
5-(benzyloxy)-3-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine

Guidance literature:: benzyl alcohol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 1h; Inert atmosphere;

3,5-dibromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/acsmedchemlett.7b00404

Reference yield:

: 35486-42-1
2-amino-3,5-dibromopyridine

: 110-13-4
2,5-hexanedione

: 1262133-29-8
5-(benzyloxy)-3-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / toluene / 2.5 h / Reflux; Enzymatic reaction

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

With sodium hydride; toluene-4-sulfonic acid; In N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/acsmedchemlett.7b00404