2-methyl-2-(1H-pyrazol-1-yl)propanoic acid

Base Information

Chemical Name:2-methyl-2-(1H-pyrazol-1-yl)propanoic acid
CAS No.:851975-10-5
Molecular Formula:C₇H₁₀N₂O₂
Molecular Weight:154.169
Hs Code.:2933199090
European Community (EC) Number:838-120-8
DSSTox Substance ID:DTXSID501296540
Mol file:851975-10-5.mol

Synonyms:2-methyl-2-(1H-pyrazol-1-yl)propanoic acid;851975-10-5;2-methyl-2-pyrazol-1-ylpropanoic acid;SCHEMBL3095800;SZGVDJHDIPSUSA-UHFFFAOYSA-N;DTXSID501296540;BJB97510;MFCD03844849;AKOS005069306;2-methyl-2-(1H-pyrazol-1-yl)propanoicacid;CS-0173627;EN300-66197;alpha,alpha-Dimethyl-1H-pyrazole-1-acetic acid;10W-0717;Z803460280

Suppliers and Price of 2-methyl-2-(1H-pyrazol-1-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Methyl-2-(1H-pyrazol-1-yl)propanoic acid 97%
1g
$ 454.00

Matrix Scientific
2-Methyl-2-(1H-pyrazol-1-yl)propanoic acid 97%
500mg
$ 362.00

Ambeed
2-Methyl-2-(1H-pyrazol-1-yl)propanoicacid 97%
1g
$ 141.00

Ambeed
2-Methyl-2-(1H-pyrazol-1-yl)propanoicacid 97%
250mg
$ 57.00

Ambeed
2-Methyl-2-(1H-pyrazol-1-yl)propanoicacid 97%
5g
$ 494.00

Alichem
2-Methyl-2-(1h-pyrazol-1-yl)propanoicacid
1g
$ 542.23

AK Scientific
2-Methyl-2-(1H-pyrazol-1-yl)propanoicacid
2.5g
$ 1272.00

AK Scientific
2-Methyl-2-(1H-pyrazol-1-yl)propanoicacid
1g
$ 674.00

Total 6 raw suppliers

Chemical Property of 2-methyl-2-(1H-pyrazol-1-yl)propanoic acid

Chemical Property:

Melting Point:107-111°C
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:154.074227566
Heavy Atom Count:11
Complexity:168

Purity/Quality:

97% ^*data from raw suppliers

2-Methyl-2-(1H-pyrazol-1-yl)propanoic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C(=O)O)N1C=CC=N1

Technology Process of 2-methyl-2-(1H-pyrazol-1-yl)propanoic acid

There total 1 articles about 2-methyl-2-(1H-pyrazol-1-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 288-13-1
NH-pyrazole

: 2052-01-9
2-bromo-2-methylpropionic acid

: 851975-10-5
2-methyl-2-(1H-pyrazol-1-yl)propanoic acid

Guidance literature:: With triethylamine; In 2-methyltetrahydrofuran;

Reference yield:

: 851975-10-5
2-methyl-2-(1H-pyrazol-1-yl)propanoic acid

: N-(biphenyl-4-yl)-3-{[2-methyl-2-(1H-pyrazol-1-yl)propanoyl]amino}-4-(trifluoromethyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / dichloromethane / 5 h / 50 °C

2: N,N-dimethyl-formamide / 20 °C

With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 851975-10-5
2-methyl-2-(1H-pyrazol-1-yl)propanoic acid

: 1201657-32-0
ethyl 2-methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid

2: N-Bromosuccinimide / 2-methyltetrahydrofuran

3: potassium acetate; XPhos / ethanol / 5 h / 75 °C / Inert atmosphere

With N-Bromosuccinimide; sulfuric acid; potassium acetate; XPhos; In 2-methyltetrahydrofuran; ethanol; 3: |Miyaura Borylation Reaction;