3-[(Dimethylamino)methyl]-4-[methyl(phenyl)amino]furan-2(5H)-one

Base Information

Chemical Name:3-[(Dimethylamino)methyl]-4-[methyl(phenyl)amino]furan-2(5H)-one
CAS No.:119648-09-8
Molecular Formula:C14H18N2O2
Molecular Weight:246.3
Hs Code.:
DSSTox Substance ID:DTXSID50702047
Nikkaji Number:J187.045I
Wikidata:Q63392927
Mol file:119648-09-8.mol

Synonyms:119648-09-8;DTXSID50702047;FTYPFXXOUHSABS-UHFFFAOYSA-N;Q63392927;3-[(Dimethylamino)methyl]-4-(methylphenylamino)-2(5H)-furanone;3-[(Dimethylamino)methyl]-4-[methyl(phenyl)amino]furan-2(5H)-one;3-DIMETHYLAMINOMETHYL-4-METHYLPHENYLAMINO-2(5H)-FURANONE

Suppliers and Price of 3-[(Dimethylamino)methyl]-4-[methyl(phenyl)amino]furan-2(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-[(Dimethylamino)methyl]-4-[methyl(phenyl)amino]furan-2(5H)-one

Chemical Property:

PSA：32.78000
LogP:1.49530
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:246.136827821
Heavy Atom Count:18
Complexity:344

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC1=C(COC1=O)N(C)C2=CC=CC=C2

Technology Process of 3-[(Dimethylamino)methyl]-4-[methyl(phenyl)amino]furan-2(5H)-one

There total 4 articles about 3-[(Dimethylamino)methyl]-4-[methyl(phenyl)amino]furan-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.3%

: 33797-51-2
eschenmoser's salt

: 121694-87-9
4-(N-methylanilino)-2(5H)-furanone

: 119648-09-8
3-(N,N-dimethylaminoethyl)-4-(N-methylanilino)-2(5H)-furanone

Guidance literature:: With potassium carbonate; In 1,2-dimethoxyethane; for 3h; Ambient temperature;
DOI:10.3987/COM-88-4594

Reference yield:

: 62-53-3
aniline

: 119648-09-8
3-(N,N-dimethylaminoethyl)-4-(N-methylanilino)-2(5H)-furanone

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / acetic acid / 5 h / 115 - 120 °C

2: 97 percent / anhydrous potassium carbonate / 1,2-dimethoxy-ethane; acetone / 72 h / Ambient temperature

3: 92.3 percent / 2.) saturated potassium carbonate / 1,2-dimethoxy-ethane / 3 h / Ambient temperature

With potassium carbonate; In 1,2-dimethoxyethane; acetic acid; acetone;
DOI:10.3987/COM-88-4594

Reference yield:

: 22273-65-0
4-(phenylamino)furan-2(5H)-one

: 119648-09-8
3-(N,N-dimethylaminoethyl)-4-(N-methylanilino)-2(5H)-furanone

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / anhydrous potassium carbonate / 1,2-dimethoxy-ethane; acetone / 72 h / Ambient temperature

2: 92.3 percent / 2.) saturated potassium carbonate / 1,2-dimethoxy-ethane / 3 h / Ambient temperature

With potassium carbonate; In 1,2-dimethoxyethane; acetone;
DOI:10.3987/COM-88-4594