2-Nitro-4,6-bis(trifluoromethyl)aniline

Base Information

Chemical Name:2-Nitro-4,6-bis(trifluoromethyl)aniline
CAS No.:320-21-8
Molecular Formula:C8H4F6N2O2
Molecular Weight:274.1199792
Hs Code.:
DSSTox Substance ID:DTXSID00707724
Wikidata:Q82641661
Mol file:320-21-8.mol

Synonyms:2-Nitro-4,6-bis(trifluoromethyl)aniline;320-21-8;2,4-Bis(trifluoromethyl)-6-nitroaniline;SCHEMBL9173191;DTXSID00707724;INFTUELYTTXWBW-UHFFFAOYSA-N;MFCD25962254;BS-49842;CS-0181586;A875740

Suppliers and Price of 2-Nitro-4,6-bis(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Nitro-4,6-bis(trifluoromethyl)aniline 97%
5g
$ 669.00

Alichem
2,4-Bis(trifluoromethyl)-6-nitroaniline
1g
$ 1519.80

Total 16 raw suppliers

Chemical Property of 2-Nitro-4,6-bis(trifluoromethyl)aniline

Chemical Property:

Melting Point:69-70 °C
Boiling Point:229.2±40.0 °C(Predicted)
PKA:-5.24±0.25(Predicted)
PSA：71.84000
Density:1.607±0.06 g/cm3(Predicted)
LogP:4.31900
Storage Temp.:2-8°C(protect from light)
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:0
Exact Mass:274.01769635
Heavy Atom Count:18
Complexity:323

Purity/Quality:

97% ^*data from raw suppliers

2-Nitro-4,6-bis(trifluoromethyl)aniline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1C(F)(F)F)N)[N+](=O)[O-])C(F)(F)F

Technology Process of 2-Nitro-4,6-bis(trifluoromethyl)aniline

There total 4 articles about 2-Nitro-4,6-bis(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-(2-Nitro-4,6-bis-trifluoromethyl-phenyl)-acetamide

: 320-21-8
2-nitro-4,6-bis-trifluoromethyl-aniline

Guidance literature:: With hydrogenchloride; Heating;
DOI:10.1021/jm00022a003

Reference yield:

: 367-71-5
2,4-bis(trifluoromethyl)aniline

: 320-21-8
2-nitro-4,6-bis-trifluoromethyl-aniline

Guidance literature:: Multi-step reaction with 3 steps

1: 12 h / 25 °C

2: concd. H₂SO₄, concd. HNO₃ / 0 - 20 °C

3: concd. HCl / Heating

With hydrogenchloride; sulfuric acid; nitric acid;
DOI:10.1021/jm00022a003

Reference yield:

: N-(2,4-bis(trifluoromethyl)phenyl)acetamide

: 320-21-8
2-nitro-4,6-bis-trifluoromethyl-aniline

Guidance literature:: Multi-step reaction with 2 steps

1: concd. H₂SO₄, concd. HNO₃ / 0 - 20 °C

2: concd. HCl / Heating

With hydrogenchloride; sulfuric acid; nitric acid;
DOI:10.1021/jm00022a003