Difluoro-quinolin-6-yl-acetic acid hydrazide

Base Information

Chemical Name:Difluoro-quinolin-6-yl-acetic acid hydrazide
CAS No.:943541-39-7
Molecular Formula:C11H9F2N3O
Molecular Weight:237.209
Hs Code.:
Mol file:943541-39-7.mol

Synonyms:Difluoro-quinolin-6-yl-acetic acid hydrazide;2,2-difluoro-2-quinolin-6-ylacetohydrazide

Suppliers and Price of Difluoro-quinolin-6-yl-acetic acid hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2,2-Difluoro-2-(quinolin-6-yl)acetohydrazide 97%
250mg
$ 342.00

Crysdot
2,2-Difluoro-2-(quinolin-6-yl)acetohydrazide 97%
1g
$ 450.00

Chemenu
2,2-Difluoro-2-(quinolin-6-yl)acetohydrazide 95%+
1g
$ 425.00

Alichem
2,2-Difluoro-2-(quinolin-6-yl)acetohydrazide
1g
$ 482.30

Total 3 raw suppliers

Chemical Property of Difluoro-quinolin-6-yl-acetic acid hydrazide

Chemical Property:

Boiling Point:459.1±45.0 °C(Predicted)
PKA:8.90±0.50(Predicted)
PSA：71.50000
Density:1.387±0.06 g/cm3(Predicted)
LogP:2.85710
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

2,2-Difluoro-2-(quinolin-6-yl)acetohydrazide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Difluoro-quinolin-6-yl-acetic acid hydrazide

There total 5 articles about Difluoro-quinolin-6-yl-acetic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 943541-38-6
2,2-difluoro-2-(quinolin-6-yl)acetic acid methyl ester

: 943541-39-7
2,2-difluoro-2-(quinolin-6-yl)acetic acid hydrazide

Guidance literature:: With hydrazine; In methanol; for 2h; Product distribution / selectivity; Heating / reflux;

Reference yield: 91.0%

: 943541-40-0
ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate

: 943541-39-7
2,2-difluoro-2-(quinolin-6-yl)acetic acid hydrazide

Guidance literature:: With hydrazine; In ethanol; at 20 ℃; for 0.166667h;

Reference yield:

: 13327-31-6
6-iodoquinoline

: 943541-39-7
2,2-difluoro-2-(quinolin-6-yl)acetic acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: copper / dimethyl sulfoxide / 15 h / 55 °C / Inert atmosphere

2: hydrazine hydrate / methanol / 0.5 h / 45 °C

With copper; hydrazine hydrate; In methanol; dimethyl sulfoxide;