4,4'-BISBENZHYDRAZIDE

Base Information

• Chemical Name: 4,4'-BISBENZHYDRAZIDE
• CAS No.: 4073-75-0
• Molecular Formula: C14H14N4O2
• Molecular Weight: 270.29
• Mol file: 4073-75-0.mol

Synonyms:DIPHENYL-4,4'DICARBOHYDRAZIDE;DIPHENYL-4,4'-DICARBOHYDRAZINE;4,4'-BISBENZHYDRAZIDE;4,4'-Biphenyldicarboxylic dihydrazide

Chemical Property of 4,4'-BISBENZHYDRAZIDE

Chemical Property:

• PSA: 110.24000
• LogP: 2.74300

Purity/Quality:

99% ^*data from raw suppliers

4,4''-bis-Benzhydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-BISBENZHYDRAZIDE

There total 2 articles about 4,4'-BISBENZHYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4,4'-biphenyldicarboxylic acid dimethyl ester (792-74-5) → 1,1′-Biphenyl-4,4′-dicarbohydrazide (4073-75-0)

Guidance literature:

With hydrazine hydrate; at 70 ℃; for 24h;

DOI:10.1002/anie.201500400

Reference yield: 76.0%

4,4'-diphenic acid (787-70-2) + hydrazine (302-01-2,78206-91-4,119775-10-9,75013-58-0) → 1,1′-Biphenyl-4,4′-dicarbohydrazide (4073-75-0)

Guidance literature:

4,4'-diphenic acid; With 2-(6-chloro-1H-benzotriazole-1-yl)-1,1,3,3-tetramethylaminium hexafluoro-phosphate; triethylamine; In acetonitrile; at 20 ℃; for 5h;

hydrazine; With triethylamine; In acetonitrile; at 20 ℃; for 16h;

DOI:10.1039/c3dt50578b

Reference yield: 92.0%

1,1′-Biphenyl-4,4′-dicarbohydrazide (4073-75-0) + salicylaldehyde (90-02-8) → 1,1’-biphenyl-4,4'-dicarboxylic acid, bis-((2-hydroxyphenyl)methylidene)hydrazone

Guidance literature:

With acetic acid; In ethanol; for 20h; Reflux;

DOI:10.1002/anie.201500400

upstream raw materials:

4,4'-biphenyldicarboxylic acid dimethyl ester

4,4'-diphenic acid

hydrazine

Downstream raw materials:

((C₆H₄)C(O)NHNCH(C₆H₄)OH)2

1,1′-Biphenyl-4,4′-dicarboxylic acid, bis-(2-pyridinylmethylene)-hydrazide

N,N'-bis[4-hydroxybenzylidene]biphenyl-4,4'-dicarbohydrazide

N,N'-bis[3-hydroxy-4-methoxybenzylidene]biphenyl-4,4'-dicarbohydrazide