2-M-TOLYL-OXAZOL-4-YL-METHYLAMINE

Base Information

• Chemical Name: 2-M-TOLYL-OXAZOL-4-YL-METHYLAMINE
• CAS No.: 885273-21-2
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.229
• Hs Code.: 2934999090
• Mol file: 885273-21-2.mol

Synonyms:C-(2-M-TOLYL-OXAZOL-4-YL)-METHYLAMINE;2-M-TOLYL-OXAZOL-4-YL-METHYLAMINE;(2-(M-Tolyl)oxazol-4-yl)MethanaMine

Chemical Property of 2-M-TOLYL-OXAZOL-4-YL-METHYLAMINE

Chemical Property:

• PSA: 52.05000
• LogP: 2.80900

Purity/Quality:

98%min ^*data from raw suppliers

2-m-Tolyl-oxazol-4-yl-methylamine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-M-TOLYL-OXAZOL-4-YL-METHYLAMINE

There total 3 articles about 2-M-TOLYL-OXAZOL-4-YL-METHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H14N2O3 → C11H12N2O (885273-21-2)

Guidance literature:

With hydrazine hydrate; In ethanol; Inert atmosphere; Reflux;

DOI:10.1007/s11696-019-00932-5

Reference yield:

C11H10ClNO (1038708-57-4) → C11H12N2O (885273-21-2)

Guidance literature:

C₁₁H₁₀ClNO; With potassium phtalimide; In N,N-dimethyl-formamide; at 80 ℃;

With hydrazine hydrate; In ethanol; at 20 ℃;

DOI:10.1016/j.bmc.2019.05.029

Reference yield:

m-toluamide (618-47-3) → C11H12N2O (885273-21-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 130 °C

2.1: potassium phtalimide / N,N-dimethyl-formamide / 80 °C

2.2: 20 °C

With potassium phtalimide; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2019.05.029

upstream raw materials:

m-toluamide

C₁₁H₁₀ClNO

Refernces

• 1、 Yan, Zhongzhong,Liu, Aiping,Ou, Yingcan,Li, Jianming,Yi,Zhang, Ning,Liu, Minhua,Huang, Lu,Ren, Jianwei,Liu, Weidong,Hu, Aixi. "Design, synthesis and fungicidal activity evaluation of novel pyrimidinamine derivatives containing phenyl-thiazole/oxazole moiety". . p. 3218 - 3228. Retrieved 2019/06/05.