8-METHYL-2-PHENYL-4-QUINOLINOL

Base Information

• Chemical Name: 8-METHYL-2-PHENYL-4-QUINOLINOL
• CAS No.: 92855-38-4
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.285
• Hs Code.: 2933499090
• Mol file: 92855-38-4.mol

Synonyms:8-METHYL-2-PHENYL-4-QUINOLINOL;4-Hydroxy-8-methyl-2-phenylquinoline

Chemical Property of 8-METHYL-2-PHENYL-4-QUINOLINOL

Chemical Property:

• Vapor Pressure: 1.1E-06mmHg at 25°C
• Boiling Point: 402.3°C at 760 mmHg
• Flash Point: 159.6°C
• PSA: 33.12000
• Density: 1.173g/cm³
• LogP: 3.91580

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Hydroxy-8-methyl-2-phenylquinoline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-METHYL-2-PHENYL-4-QUINOLINOL

There total 9 articles about 8-METHYL-2-PHENYL-4-QUINOLINOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) + o-toluidine (95-53-4) → 8-methyl-2-phenyl-quinolin-4-ol (92855-38-4)

Guidance literature:

With hydrogenchloride; und Behandeln des Reaktionsprodukts mit einem Gemisch von Biphenyl und Diphenylaether bei Siedetemperatur;

DOI:10.1021/ja01187a025

Reference yield:

4-hydroxy-8-methyl-2-phenyl-quinoline-3-carboxylic acid → 8-methyl-2-phenyl-quinolin-4-ol (92855-38-4)

Guidance literature:

With paraffin oil; at 270 - 275 ℃;

Reference yield:

(8-methyl-2-phenyl-[4]quinolyl)-phenyl-amine → 8-methyl-2-phenyl-quinolin-4-ol (92855-38-4)

Guidance literature:

With potassium hydroxide; at 270 - 290 ℃;

upstream raw materials:

3-amino-2-(α-o-tolylimino-benzyl)-crotonic acid methyl ester

3-amino-2-(α-o-tolylimino-benzyl)-crotonic acid ethyl ester

ethyl 3-oxo-3-phenylpropionate

o-toluidine

Downstream raw materials:

4-Chlor-8-methyl-2-phenyl-chinolin