ETHYL 5-METHOXYPYRIDINE-3-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 5-METHOXYPYRIDINE-3-CARBOXYLATE
• CAS No.: 20826-01-1
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.191
• Hs Code.: 2933399090
• Mol file: 20826-01-1.mol

Synonyms:ETHYL 5-METHOXYPYRIDINE-3-CARBOXYLATE

Chemical Property of ETHYL 5-METHOXYPYRIDINE-3-CARBOXYLATE

Chemical Property:

• Vapor Pressure: 0.00814mmHg at 25°C
• Boiling Point: 267.5°C at 760 mmHg
• Flash Point: 115.6°C
• PSA: 48.42000
• Density: 1.124g/cm³
• LogP: 1.26690

Purity/Quality:

97% ^*data from raw suppliers

ethyl5-methoxypyridine-3-carboxylate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 5-METHOXYPYRIDINE-3-CARBOXYLATE

There total 1 articles about ETHYL 5-METHOXYPYRIDINE-3-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Ethyl 5-methoxynicotinate (20826-01-1)

Guidance literature:

5-Hydroxy-nicotinsaeure-ethylester, Diazomethan;

Reference yield:

Ethyl 5-methoxynicotinate (20826-01-1) → N-[3-(5-hydroxy-3-pyridyl)acryloyl]4-(4-diphenylmethyl-1-piperazinyl)butylamine (118420-39-6)

Guidance literature:

Multi-step reaction with 5 steps

1: LiAlH₄ / diethyl ether / Heating

2: CrO₃, pyridine / Heating

3: piperidine / pyridine / 100 °C

4: 1.) ethyl chlorocarbonate

5: 20 percent / BBr₃ / CH₂Cl₂ / Ambient temperature

With piperidine; pyridine; chromium(VI) oxide; lithium aluminium tetrahydride; chloroformic acid ethyl ester; boron tribromide; In pyridine; diethyl ether; dichloromethane;

DOI:10.1021/jm00123a012

Reference yield:

Ethyl 5-methoxynicotinate (20826-01-1) → (E)-N-[4-(4-Benzhydryl-piperazin-1-yl)-butyl]-3-(5-methoxy-pyridin-3-yl)-acrylamide (118420-38-5)

Guidance literature:

Multi-step reaction with 4 steps

1: LiAlH₄ / diethyl ether / Heating

2: CrO₃, pyridine / Heating

3: piperidine / pyridine / 100 °C

4: 1.) ethyl chlorocarbonate

With piperidine; pyridine; chromium(VI) oxide; lithium aluminium tetrahydride; chloroformic acid ethyl ester; In pyridine; diethyl ether;

DOI:10.1021/jm00123a012

Downstream raw materials:

(5-methoxypyridin-3-yl)methanol

5-methoxypyridine-3-carboxaldehyde

N-[3-(5-hydroxy-3-pyridyl)acryloyl]4-(4-diphenylmethyl-1-piperazinyl)butylamine

(E)-N-[4-(4-Benzhydryl-piperazin-1-yl)-butyl]-3-(5-methoxy-pyridin-3-yl)-acrylamide