N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide

Base Information

• Chemical Name: N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide
• CAS No.: 5317-95-3
• Molecular Formula: C15H14BrNO3S
• Molecular Weight: 368.251
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID40586237
• Wikidata: Q82478329
• Mol file: 5317-95-3.mol

Synonyms:5317-95-3;N-[4-(2-BROMOACETYL)PHENYL]-4-METHYLBENZENESULFONAMIDE;N-(4-(2-Bromoacetyl)phenyl)-4-methylbenzenesulfonamide;JCAMJGYWGVGROB-UHFFFAOYSA-N;N-(4-bromoacetylphenyl)-4-methylphenylsulphonamide;SCHEMBL7406463;DTXSID40586237;AKOS000269390;4'-(2-bromoacetyl)-p-toluenesulfonanilide;DB-320749;N-[4-(bromoacetyl)phenyl]-4-methylbenzenesulfonamide;N-[4-(Bromoacetyl)phenyl]-4-methylbenzene-1-sulfonamide

Chemical Property of N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide

Chemical Property:

• PSA: 71.62000
• LogP: 4.52720
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 366.98778
• Heavy Atom Count: 21
• Complexity: 444

Purity/Quality:

97% ^*data from raw suppliers

N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)C(=O)CBr
• Uses: N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide can be used for preparation of heterocyclyl-substituted piperazines for the prevention or treatment of a disease mediated by the binding of adhesion molecules to GPIIb/IIIa.

Technology Process of N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide

There total 3 articles about N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(p-toluenesulfonylamino)acetophenone (5317-94-2) → N-(4-bromoacetylphenyl)-4-methylphenylsulphonamide (5317-95-3)

Guidance literature:

With bromine; dibenzoyl peroxide; In diethyl ether;

DOI:10.1021/jm00319a023

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → N-(4-bromoacetylphenyl)-4-methylphenylsulphonamide (5317-95-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / tetrahydrofuran / 12 h / 20 °C

2: phenyltrimethylammonium tribromide / tetrahydrofuran / 12 h / 20 °C

With pyridine; phenyltrimethylammonium tribromide; In tetrahydrofuran;

DOI:10.1016/j.ejmech.2017.11.023

Reference yield:

p-aminobenzophenone (99-92-3) → N-(4-bromoacetylphenyl)-4-methylphenylsulphonamide (5317-95-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / tetrahydrofuran / 12 h / 20 °C

2: phenyltrimethylammonium tribromide / tetrahydrofuran / 12 h / 20 °C

With pyridine; phenyltrimethylammonium tribromide; In tetrahydrofuran;

DOI:10.1016/j.ejmech.2017.11.023

upstream raw materials:

4-(p-toluenesulfonylamino)acetophenone

p-toluenesulfonyl chloride

p-aminobenzophenone

Downstream raw materials:

N-[4-[2-[4-(4-pyridyl)piperazin-1-yl]acetyl]phenyl]-4-methylphenylsulphonamide

C₁₇H₁₇NO₄S₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 5317-95-3 N-[4-(2-Bromoacetyl)phenyl]-4-methylbenzenesulfonamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send