4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

Base Information

Chemical Name:4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol
CAS No.:1344738-07-3
Molecular Formula:C₁₄H₁₈ClN₃OS
Molecular Weight:0
Hs Code.:
Mol file:1344738-07-3.mol

Synonyms:4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

Suppliers and Price of 4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

There total 5 articles about 4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 876299-32-0
4,4-dimethyl-5-(methylthio)-3-oxopentanenitrile

: 243141-12-0
3-chloro-4-hydroxyphenylhydrazine hydrochloride

: 1344738-07-3
4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

Guidance literature:: With hydrogenchloride; In ethanol; water; for 6h; Reflux; Inert atmosphere;
DOI:10.1021/jm200677b

Reference yield:

: 876299-31-9
methyl 2,2-dimethyl-3-(methylthio)propanoate

: 1344738-07-3
4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 5 h / 75 °C / Inert atmosphere

2: hydrogenchloride / ethanol; water / 6 h / Reflux; Inert atmosphere

With hydrogenchloride; sodium hydride; In tetrahydrofuran; ethanol; water; mineral oil;
DOI:10.1021/jm200677b

Reference yield:

: 846038-01-5
methyl 2,2-dimethyl-3-((methylsulfonyl)oxy)propanoate

: 1344738-07-3
4-{5-amino-3-[1,1-dimethyl-2-(methylthio)ethyl]-1H-pyrazol-1-yl}-2-chlorophenol

Guidance literature:: Multi-step reaction with 3 steps

1: methanol / 20 h / 50 °C / Reflux; Inert atmosphere

2: sodium hydride / tetrahydrofuran; mineral oil / 5 h / 75 °C / Inert atmosphere

3: hydrogenchloride / ethanol; water / 6 h / Reflux; Inert atmosphere

With hydrogenchloride; sodium hydride; In tetrahydrofuran; methanol; ethanol; water; mineral oil;
DOI:10.1021/jm200677b