3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine
CAS No.:1450642-40-6
Molecular Formula:C₁₈H₁₅IN₄O₂S
Molecular Weight:478.313
Hs Code.:
Mol file:1450642-40-6.mol

Synonyms:3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

Suppliers and Price of 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

There total 3 articles about 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1093676-98-2
3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine

: 98-59-9
p-toluenesulfonyl chloride

: 1450642-40-6
3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-p-tosyl-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With dmap; In dichloromethane; at 25 ℃; for 2h;
DOI:10.1016/j.bmcl.2013.06.071

Reference yield:

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 1450642-40-6
3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-p-tosyl-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / water; 1,2-dimethoxyethane / 15 h / 110 °C

2: N-iodo-succinimide / dichloromethane / 0.5 h / 25 °C

3: dmap / dichloromethane / 2 h / 25 °C

With dmap; N-iodo-succinimide; sodium carbonate; In 1,2-dimethoxyethane; dichloromethane; water;
DOI:10.1016/j.bmcl.2013.06.071

Reference yield:

: 918522-51-7
5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]-pyridine

: 1450642-40-6
3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1-p-tosyl-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / dichloromethane / 0.5 h / 25 °C

2: dmap / dichloromethane / 2 h / 25 °C

With dmap; N-iodo-succinimide; In dichloromethane;
DOI:10.1016/j.bmcl.2013.06.071