1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-

Base Information

Chemical Name:1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-
CAS No.:1093676-98-2
Molecular Formula:C11H9IN4
Molecular Weight:324.124
Hs Code.:
Mol file:1093676-98-2.mol

Synonyms:3-iodo-5-(1-methylpyrazol-4-yl)-7-azaindole;1H-Pyrrolo[2,3-b]pyridine,3-iodo-5-(1-methyl-1H-pyrazol-4-yl);3-IODO-5-(1-METHYL-1H-PYRAZOL-4-YL)-1H-PYRROLO[2,3-B]PYRIDINE;

Suppliers and Price of 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine 95+%
1g
$ 794.00

Chemenu
3-Iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine 95%
1g
$ 750.00

Alichem
3-Iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
1g
$ 861.90

Total 2 raw suppliers

Chemical Property of 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-

Chemical Property:

PSA：46.50000
LogP:2.56800

Purity/Quality:

99% ^*data from raw suppliers

3-Iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-

There total 2 articles about 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 918522-51-7
5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]-pyridine

: 1093676-98-2
3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With N-iodo-succinimide; In acetonitrile; at 50 ℃; for 2h;
DOI:10.1021/acs.jmedchem.1c00674

Reference yield:

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 1093676-98-2
3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / water; 1,2-dimethoxyethane / 15 h / 110 °C

2: N-iodo-succinimide / dichloromethane / 0.5 h / 25 °C

With N-iodo-succinimide; sodium carbonate; In 1,2-dimethoxyethane; dichloromethane; water;
DOI:10.1016/j.bmcl.2013.06.071