5-Acetyl-2-methoxybenzenesulfonyl chloride

Base Information

Chemical Name:5-Acetyl-2-methoxybenzenesulfonyl chloride
CAS No.:85276-41-1
Molecular Formula:C9H9ClO4S
Molecular Weight:248.687
Hs Code.:2914700090
DSSTox Substance ID:DTXSID30406137
Wikidata:Q82211031
Mol file:85276-41-1.mol

Synonyms:85276-41-1;5-acetyl-2-methoxybenzenesulfonyl chloride;5-acetyl-2-methoxybenzene-1-sulfonyl chloride;BENZENESULFONYL CHLORIDE, 5-ACETYL-2-METHOXY-;DTXSID30406137;AKOS002662789;CS-0248447;EN300-399151

Suppliers and Price of 5-Acetyl-2-methoxybenzenesulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-ACETYL-2-METHOXY-BENZENESULFONYL CHLORIDE 95.00%
5MG
$ 497.24

AK Scientific
5-Acetyl-2-methoxybenzenesulfonylchloride
1g
$ 676.00

Total 4 raw suppliers

Chemical Property of 5-Acetyl-2-methoxybenzenesulfonyl chloride

Chemical Property:

PSA：68.82000
LogP:2.90610
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:247.9910076
Heavy Atom Count:15
Complexity:333

Purity/Quality:

99% ^*data from raw suppliers

5-ACETYL-2-METHOXY-BENZENESULFONYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1)OC)S(=O)(=O)Cl

Technology Process of 5-Acetyl-2-methoxybenzenesulfonyl chloride

There total 3 articles about 5-Acetyl-2-methoxybenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 85276-41-1
5-acetyl-2-methoxybenzenesulfonyl chloride

Guidance literature:: With chlorosulfonic acid; thionyl chloride; at 20 ℃; for 26h;
DOI:10.1016/j.ejmech.2019.05.013

Reference yield:

: 6318-64-5
1-(3-amino-4-methoxyphenyl)ethan-1-one

: 85276-41-1
5-acetyl-2-methoxybenzenesulfonyl chloride

Guidance literature:: With hydrogenchloride; sulfur dioxide; sodium nitrite; Yield given. Multistep reaction; 1.) AcOH, 5 deg C, 30 min 2.) AcOH, 0-5 deg C;
DOI:10.1248/cpb.30.4092

Reference yield:

: 6277-38-9
1-(4-methoxy-3-nitrophenyl)ethanone

: 85276-41-1
5-acetyl-2-methoxybenzenesulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: iron; ammonium chloride / water; ethanol / 50 - 80 °C

2.1: hydrogenchloride; acetic acid; sodium nitrite / water / -10 - -5 °C

2.2: 10 °C

With hydrogenchloride; iron; ammonium chloride; acetic acid; sodium nitrite; In ethanol; water;
DOI:10.1021/jm501504k