3-Phenyl-1H-benzofuro[3,2-c]pyrazole

Base Information

Chemical Name:3-Phenyl-1H-benzofuro[3,2-c]pyrazole
CAS No.:34823-86-4
Molecular Formula:C15H10N2O
Molecular Weight:234.257
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10188363
Nikkaji Number:J1.952.206G
Wikidata:Q27077928
Pharos Ligand ID:6929NKMS9JTV
ChEMBL ID:CHEMBL406375
Mol file:34823-86-4.mol

Synonyms:GTP 14564;GTP-14564;GTP14564

Suppliers and Price of 3-Phenyl-1H-benzofuro[3,2-c]pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
GTP 14564
10mg
$ 403.00

TRC
GTP14564
1mg
$ 40.00

Tocris
GTP14564 ≥99%(HPLC)
10
$ 122.00

Cayman Chemical
GTP 14564 ≥98%
5mg
$ 113.00

Cayman Chemical
GTP 14564 ≥98%
1mg
$ 45.00

Cayman Chemical
GTP 14564 ≥98%
500μg
$ 25.00

American Custom Chemicals Corporation
GTP 14564 95.00%
10MG
$ 685.21

American Custom Chemicals Corporation
GTP 14564 95.00%
1MG
$ 160.65

AK Scientific
3-Phenyl-1H-benzofuro[3,2-c]pyrazole
5mg
$ 252.00

Total 14 raw suppliers

Chemical Property of 3-Phenyl-1H-benzofuro[3,2-c]pyrazole

Chemical Property:

Vapor Pressure:3.56E-08mmHg at 25°C
Melting Point:222-223 °C
Refractive Index:1.738
Boiling Point:459.1 °C at 760 mmHg
PKA:12.72±0.30(Predicted)
Flash Point:240.7 °C
PSA：41.82000
Density:1.321 g/cm³
LogP:3.97610
Storage Temp.:Store at +4°C
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:234.079312947
Heavy Atom Count:18
Complexity:303

Purity/Quality:

99% ^*data from raw suppliers

GTP 14564 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NNC3=C2OC4=CC=CC=C43
Description GTP 14564 is an inhibitor of class III receptor tyrosine kinases (IC50s = 0.3 μM for c-Fms, c-Kit, ITD-FLT3 and 1 μM for PDGFRβ). It is without effect against a panel of non-receptor tyrosine and serine/threonine kinases. GTP 14564 blocks the proliferation of leukemia cells stimulated with FLT3 ligand by preventing the activation of STAT5.
Uses GTP 14564 is a class III receptor tyrosine kinase (RTK) inhibitor.

Technology Process of 3-Phenyl-1H-benzofuro[3,2-c]pyrazole

There total 8 articles about 3-Phenyl-1H-benzofuro[3,2-c]pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%