1,2-Bis(5-bromopyridin-2-yl)disulfane

Base Information

• Chemical Name: 1,2-Bis(5-bromopyridin-2-yl)disulfane
• CAS No.: 872273-36-4
• Molecular Formula: C10H6Br2N2S2
• Molecular Weight: 378.111
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID10682452
• Nikkaji Number: J2.721.540H
• Wikidata: Q82606844
• Mol file: 872273-36-4.mol

Synonyms:1,2-Bis(5-bromopyridin-2-yl)disulfane;872273-36-4;5-bromo-2-[(5-bromopyridin-2-yl)disulfanyl]pyridine;SCHEMBL11731794;DTXSID10682452;2,2'-Dithiobis(5-bromopyridine);XJB27336;MFCD16660320;AKOS015834681;2,2'-Disulfanediylbis(5-bromopyridine);BS-24126;CS-0158752;A862714

Chemical Property of 1,2-Bis(5-bromopyridin-2-yl)disulfane

Chemical Property:

• PSA: 76.38000
• LogP: 4.80100
• Storage Temp.: Room temperature.
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 377.83187
• Heavy Atom Count: 16
• Complexity: 199

Purity/Quality:

97% ^*data from raw suppliers

1,2-Bis(5-bromopyridin-2-yl)disulfane 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC=C1Br)SSC2=NC=C(C=C2)Br

Technology Process of 1,2-Bis(5-bromopyridin-2-yl)disulfane

There total 7 articles about 1,2-Bis(5-bromopyridin-2-yl)disulfane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

5-bromo-2-mercaptopyridine (56673-34-8) → 5-bromo-2-(2-(5-bromopyridin-2-yl)disulfanyl)pyridine (872273-36-4)

Guidance literature:

With aluminum oxide; In neat (no solvent); for 0.333333h; chemoselective reaction; Milling;

DOI:10.1039/c3ra41996g

Reference yield: 91.0%

5-bromopyridine-2(1H)-thione (56673-34-8) → 5-bromo-2-(2-(5-bromopyridin-2-yl)disulfanyl)pyridine (872273-36-4)

Guidance literature:

With sulfuryl dichloride; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/jo070408f DOI:10.1002/adsc.200600566

Reference yield: 82.0%

2-iodo-5-bromopyridine (223463-13-6) → 5-bromo-2-(2-(5-bromopyridin-2-yl)disulfanyl)pyridine (872273-36-4)

Guidance literature:

With indium(III) oxide; ammonia; water; sulfur; In ethanol; at 60 ℃; Green chemistry;

DOI:10.1080/00397911.2018.1466335

upstream raw materials:

5-bromo-2-mercaptopyridine

5-bromopyridine-2(1H)-thione

5-bromo-2-chloropyridine

5-bromopyridin-2-ol

Downstream raw materials:

5-bromo-2-(phenylthio)pyridine