6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester

Base Information

Chemical Name:6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester
CAS No.:85418-73-1
Molecular Formula:C₁₄H₁₅NO₃
Molecular Weight:245.278
Hs Code.:2933499090
DSSTox Substance ID:DTXSID00350618
ChEMBL ID:CHEMBL206540
Mol file:85418-73-1.mol

Synonyms:85418-73-1;6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester;GNF-PF-4421;ethyl 6-ethyl-4-hydroxyquinoline-3-carboxylate;ethyl 6-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylate;ethyl 6-ethyl-4-oxo-1H-quinoline-3-carboxylate;MMV007116;111185-65-0;CHEMBL206540;MFCD00487276;AURORA 17945;starbld0045634;Oprea1_408052;Oprea1_563397;SCHEMBL7291769;SCHEMBL11066821;DTXSID00350618;ZFOFJXFVCJQXBL-UHFFFAOYSA-N;BDBM50479298;MFCD07629412;NSC766469;STK791819;STK942448;AKOS001717599;AKOS002674049;AB06331;NSC-766469;NS-03531;3-ethoxycarbonyl-6-ethyl-4(1H)-quinolone;CS-0456267;FT-0749824;ethyl 4-hydroxy-6-ethyl-3-quinoline-carboxylate;SR-01000511951;SR-01000511951-1

Suppliers and Price of 6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-ETHYL-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 95.00%
5MG
$ 499.73

Total 5 raw suppliers

Chemical Property of 6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester

Chemical Property:

Vapor Pressure:6.16E-06mmHg at 25°C
Boiling Point:378.7°C at 760 mmHg
Flash Point:182.8°C
PSA：59.42000
Density:1.184g/cm³
LogP:2.67950
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:245.10519334
Heavy Atom Count:18
Complexity:375

Purity/Quality:

98%Min ^*data from raw suppliers

6-ETHYL-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC2=C(C=C1)NC=C(C2=O)C(=O)OCC

Technology Process of 6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester

There total 6 articles about 6-Ethyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 111186-10-8
2-(((4-ethylphenyl)amino)methylene)diethyl malonate

: 111185-65-0,85418-73-1
ethyl 6-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylate

Guidance literature:: With polyphosphoric acid; at 100 ℃;

Reference yield: 77.0%

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 589-16-2
4-aminoethylbenzene

: 111185-65-0,85418-73-1
ethyl 6-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylate

Guidance literature:: diethyl 2-ethoxymethylenemalonate; 4-aminoethylbenzene; In neat (no solvent); at 120 ℃; for 1h; Inert atmosphere;

With Eaton′s Reagent; In neat (no solvent); at 130 ℃; for 1h; Inert atmosphere;
DOI:10.1002/ejic.201901036