AZD1283

Base Information

Chemical Name:AZD1283
CAS No.:919351-41-0
Molecular Formula:C₂₃H₂₆N₄O₅S
Molecular Weight:470.549
Hs Code.:
Mol file:919351-41-0.mol

Synonyms:AZD1283;6-[4-[[(Benzylsulfonyl)amino]carbonyl]piperidin-1-yl]-5-cyano-2-methylnicotinic acid ethyl ester;ethyl 6-(4-((benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate AZD1283

Suppliers and Price of AZD1283

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
AZD1283
25mg
$ 495.00

Tocris
AZD1283 ≥98%(HPLC)
10
$ 149.00

Tocris
AZD1283 ≥98%(HPLC)
50
$ 622.00

DC Chemicals
AZD1283 >98%
250 mg
$ 800.00

DC Chemicals
AZD1283 >98%
100 mg
$ 450.00

Crysdot
AZD1283 98+%
100mg
$ 1470.00

Crysdot
AZD1283 98+%
50mg
$ 1050.00

Crysdot
AZD1283 98+%
5mg
$ 158.00

Crysdot
AZD1283 98+%
10mg
$ 280.00

ChemScene
AZD1283 99.11%
10mg
$ 312.00

Total 15 raw suppliers

Chemical Property of AZD1283

Chemical Property:

PSA：137.84000
Density:1.36±0.1 g/cm3 (20 °C, 760 mmHg)
LogP:3.83768
Solubility.:insoluble in H2O; insoluble in EtOH; ≥18.15 mg/mL in DMSO

Purity/Quality:

99%, ^*data from raw suppliers

AZD1283 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses AZD 1283 is a non-nucleotide reversible antagonist of P2Y12R, which regulates platelet activation and thrombus formation.

Technology Process of AZD1283

There total 12 articles about AZD1283 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 64119-42-2
ethyl 6-chloro-5-cyano-2-methylnicotinate

: C₁₄H₁₈N₂O₅S

: 919351-41-0
ethyl 6-{4-[(benzylsulfonyl)carbamoyl]-piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl acetamide; at 60 ℃; for 18h; Inert atmosphere;
DOI:10.1021/jm400820m

Reference yield: 83.0%

: 919354-24-8
1-[3-cyano-5-(ethoxycarbonyl)-6-methylpyridin-2-yl]-piperidine-4-carboxylic acid

: 4563-33-1
phenyl-methanesulfonic acid amide

: 919351-41-0
ethyl 6-{4-[(benzylsulfonyl)carbamoyl]-piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate

Guidance literature:: 1-[3-cyano-5-(ethoxycarbonyl)-6-methylpyridin-2-yl]-piperidine-4-carboxylic acid; With 1,1'-carbonyldiimidazole; In butanone; at 20 ℃; for 7.5h; Inert atmosphere; Large scale;

phenyl-methanesulfonic acid amide; In butanone; Inert atmosphere; Large scale;
DOI:10.1021/op400288v