N-BOC-piperidine-4-carboxylic acid

Base Information

Chemical Name:N-BOC-piperidine-4-carboxylic acid
CAS No.:84358-13-4
Molecular Formula:C11H19NO4
Molecular Weight:229.276
Hs Code.:29339900
Mol file:84358-13-4.mol

Synonyms:1-tert-butoxycarbonylpiperidine-4-carboxylic acid;1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acid;1-Boc-piperidine-4-carboxylic acid;Piperidine-1,4-dicarboxylic Acid mono-tert-butyl ester;1-BOC-4-piperidine carboxylic acid;Boc-Piperidine-4-carboxylic acid;Boc-isonipecotic acid;1-N-Boc-Piperidine-4-carboxylic acid;N-tert-butoxycarbonyl-4-piperidinecarboxylic acid;Piperidine-4-carboxylic acid, N-BOC protected;1-Boc-piperidine-4-carboxylicacid;Boc-Pic(4)-OH;1-Boc-piperidine-4-carboxylic acid, 98%;1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid;1-tert-butoxycarbonylpiperidine-4-carboxylate;

Suppliers and Price of N-BOC-piperidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Boc-isonipecotic acid
50g
$ 319.00

TRC
N-Boc-IsonipecoticAcid
25g
$ 70.00

TRC
N-Boc-IsonipecoticAcid
100g
$ 125.00

TRC
N-Boc-IsonipecoticAcid
100mg
$ 45.00

TCI Chemical
1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic Acid >96.0%(GC)(T)
5g
$ 42.00

TCI Chemical
1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic Acid >96.0%(GC)(T)
25g
$ 123.00

SynQuest Laboratories
Piperidine-4-carboxylic acid, N-Boc protected 98%
100 g
$ 60.00

SynQuest Laboratories
Piperidine-4-carboxylic acid, N-Boc protected 98%
10 g
$ 10.00

SynQuest Laboratories
Piperidine-4-carboxylic acid, N-Boc protected 98%
25 g
$ 20.00

SynChem
N-tert-Butoxycarbonyl-4-piperidinecarboxylic acid 95+%
5 g
$ 20.00

Total 2 raw suppliers

Chemical Property of N-BOC-piperidine-4-carboxylic acid

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:6.15E-06mmHg at 25°C
Melting Point:148-153 °C
Boiling Point:353.2 °C at 760 mmHg
PKA:4.56±0.20(Predicted)
Flash Point:167.4 °C
PSA：66.84000
Density:1.164 g/cm³
LogP:1.65600
Storage Temp.:2-8°C
Water Solubility.:Insoluble in water.

Purity/Quality:

95-523%min ^*data from raw suppliers

N-Boc-isonipecotic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39-24/25

MSDS Files:: SDS file from LookChem

Useful:

Uses It is a pharmaceutical intermediate. he camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.

Technology Process of N-BOC-piperidine-4-carboxylic acid

There total 2 articles about N-BOC-piperidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 1146955-04-5
4-bromo-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester

: 307496-27-1
2-bromobenzylzinc(II) bromide

: 4-[(2-bromophenyl)methyl]-1-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid

: 70684-84-3
1-[(tert-butoxy)carbonyl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid

: 84358-13-4,174286-31-8
N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid

Guidance literature:: With 1,2-bis-(diphenylphosphino)ethane; cobalt(II) bromide; In tetrahydrofuran; N,N-dimethyl-formamide; at 40 ℃; for 1h;
DOI:10.1039/d0cc02734k