(3S,4S)-tert-butyl 3-(tert-butoxycarbonyl(Methyl)aMino)-4-hydroxypyrrolidine-1-carboxylate

Base Information

Chemical Name:(3S,4S)-tert-butyl 3-(tert-butoxycarbonyl(Methyl)aMino)-4-hydroxypyrrolidine-1-carboxylate
CAS No.:429673-82-5
Molecular Formula:C15H28N2O5
Molecular Weight:316.39322
Hs Code.:
Mol file:429673-82-5.mol

Synonyms:(3S,4S)-tert-butyl 3-(tert-butoxycarbonyl(Methyl)aMino)-4-hydroxypyrrolidine-1-carboxylate

Suppliers and Price of (3S,4S)-tert-butyl 3-(tert-butoxycarbonyl(Methyl)aMino)-4-hydroxypyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 10 raw suppliers

Chemical Property of (3S,4S)-tert-butyl 3-(tert-butoxycarbonyl(Methyl)aMino)-4-hydroxypyrrolidine-1-carboxylate

Chemical Property:

PSA：79.31000
LogP:1.77140

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3S,4S)-tert-butyl 3-(tert-butoxycarbonyl(Methyl)aMino)-4-hydroxypyrrolidine-1-carboxylate

There total 6 articles about (3S,4S)-tert-butyl 3-(tert-butoxycarbonyl(Methyl)aMino)-4-hydroxypyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1233960-11-6
3-hydroxy-4-methylamino-pyrrolidine-1-carboxylic acid tert-butyl ester L-(-)-malate

: 429673-82-5
(3S,4S)-1-tert-butoxycarbonyl-3-(N-tert-butoxycarbonyl)methylamino-4-hydroxypyrrolidine

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; Product distribution / selectivity;

Reference yield:

: 73286-70-1
N-(tert-butoxycarbonyl)-3-pyrroline

: 429673-82-5
(3S,4S)-1-tert-butoxycarbonyl-3-(N-tert-butoxycarbonyl)methylamino-4-hydroxypyrrolidine

Guidance literature:: Multi-step reaction with 5 steps

1: 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; water / acetonitrile / 0 - 20 °C

2: sodium hydroxide / water / 2 h / 20 °C

3: water / 20 °C

4: water; acetone / 40 - 55 °C

5: potassium carbonate / methanol / 3 h / 20 °C

With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; water; potassium carbonate; sodium hydroxide; In methanol; water; acetone; acetonitrile;

Reference yield:

: 252574-02-0
(±)-trans-tert-butyl 3-bromo-4-hydroxypyrrolidine-1-carboxylate

: 429673-82-5
(3S,4S)-1-tert-butoxycarbonyl-3-(N-tert-butoxycarbonyl)methylamino-4-hydroxypyrrolidine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / water / 2 h / 20 °C

2: water / 20 °C

3: water; acetone / 40 - 55 °C

4: potassium carbonate / methanol / 3 h / 20 °C

With potassium carbonate; sodium hydroxide; In methanol; water; acetone;