Butanamide, 4-hydroxy-

Base Information

• Chemical Name: Butanamide, 4-hydroxy-
• CAS No.: 927-60-6
• Molecular Formula: C4H9 N O2
• Molecular Weight: 103.121
• Hs Code.: 2924199090
• European Community (EC) Number: 213-155-6
• NSC Number: 19917
• UNII: D464344F6N
• DSSTox Substance ID: DTXSID5061297
• Nikkaji Number: J26.752J
• Wikidata: Q27276074
• ChEMBL ID: CHEMBL174258
• Mol file: 927-60-6.mol

Synonyms:4-hydroxybutanamide;Butanamide, 4-hydroxy-;927-60-6;4-HYDROXYBUTYRAMIDE;Butyramide, 4-hydroxy-;4-Hydroxybutyric acid amide;4-Hydroxy-butyramide;gamma-Hydroxybutyramide;.gamma.-Hydroxybutyramide;PC 621;CHEMBL174258;UNII-D464344F6N;HSDB 5769;EINECS 213-155-6;NSC 19917;NSC-19917;D464344F6N;AI3-26368;4-Hydroxybutryamide;2-(2-hydroxyethyl)acetamide;SCHEMBL80649;DTXSID5061297;NSC19917;BDBM50224828;AKOS006338508;AT20755;4-HYDROXYBUTYRIC ACID AMIDE [HSDB];FT-0721769;EN300-97058;Q27276074;Z1203578394

Chemical Property of Butanamide, 4-hydroxy-

Chemical Property:

• Vapor Pressure: 1.98E-06mmHg at 25°C
• Boiling Point: 354.1°C at 760 mmHg
• Flash Point: 167.9°C
• PSA: 63.32000
• Density: 1.11g/cm³
• LogP: -0.05550
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 103.063328530
• Heavy Atom Count: 7
• Complexity: 62.7

Purity/Quality:

4-Hydroxybutanamide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: C(CC(=O)N)CO

Technology Process of Butanamide, 4-hydroxy-

There total 6 articles about Butanamide, 4-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-trimethylsiloxybutyramide (100446-67-1) → hydroxymethyl propionamide (927-60-6)

Guidance literature:

With water;

Reference yield: 92.0%

4-butanolide (96-48-0) → hydroxymethyl propionamide (927-60-6)

Guidance literature:

With ammonium hydroxide;

Reference yield:

4-hydroxy-1-butanitrile (628-22-8) → 4-butanolide (96-48-0) + hydroxymethyl propionamide (927-60-6)

Guidance literature:

With manganese(IV) oxide; silica gel; In hexane; for 192h; Ambient temperature;

DOI:10.1016/S0040-4039(00)76229-0

upstream raw materials:

Succinimide

4-butanolide

4-hydroxy-1-butanitrile

methyl 4-hydroxybutanoate

Downstream raw materials:

Succinimide

4-Chlorobutyronitrile