-bta--Alanine, N-(methoxycarbonyl)-, 1-methylethyl ester

Base Information

• Chemical Name: -bta--Alanine, N-(methoxycarbonyl)-, 1-methylethyl ester
• CAS No.: 943827-82-5
• Molecular Formula: C₈H₁₅NO₄
• Molecular Weight: 189.211
• Mol file: 943827-82-5.mol

Synonyms:-bta--Alanine, N-(methoxycarbonyl)-, 1-methylethyl ester

Chemical Property of -bta--Alanine, N-(methoxycarbonyl)-, 1-methylethyl ester

Chemical Property:

• PSA: 64.63000
• LogP: 1.07500

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of -bta--Alanine, N-(methoxycarbonyl)-, 1-methylethyl ester

There total 4 articles about -bta--Alanine, N-(methoxycarbonyl)-, 1-methylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H11O4(1-)*K(1+) → isopropyl β-(methoxycarbonylamino)propionate (943827-82-5)

Guidance literature:

Multi-step reaction with 4 steps

1: SOCl₂ / chlorobenzene / 4 h

2: triethyl ammonium azide / 1 h

3: chlorobenzene

4: Et₃N / 12 h / 20 °C

With thionyl chloride; triethylamine; In chlorobenzene; 3: Curtius rearrangement;

DOI:10.1055/s-2007-966004

Reference yield:

C7H11O3N3 → isopropyl β-(methoxycarbonylamino)propionate (943827-82-5)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorobenzene

2: Et₃N / 12 h / 20 °C

With triethylamine; In chlorobenzene; 1: Curtius rearrangement;

DOI:10.1055/s-2007-966004

Reference yield:

isopropyl β-(chlorocarbonyl)propionate (36335-31-6) → isopropyl β-(methoxycarbonylamino)propionate (943827-82-5)

Guidance literature:

Multi-step reaction with 3 steps

1: triethyl ammonium azide / 1 h

2: chlorobenzene

3: Et₃N / 12 h / 20 °C

With triethylamine; In chlorobenzene; 2: Curtius rearrangement;

DOI:10.1055/s-2007-966004

upstream raw materials:

methanol

isopropyl β-isocyanatopropionate

isopropyl β-(chlorocarbonyl)propionate

Refernces