TERT-BUTOXYCARBONYLAMINO-INDAN-2-YL-ACETIC ACID

Base Information

Chemical Name:TERT-BUTOXYCARBONYLAMINO-INDAN-2-YL-ACETIC ACID
CAS No.:155172-73-9
Molecular Formula:C₁₆H₂₁NO₄
Molecular Weight:291.347
Hs Code.:
Mol file:155172-73-9.mol

Synonyms:TERT-BUTOXYCARBONYLAMINO-INDAN-2-YL-ACETIC ACID;1H-INDENE-2-ACETIC ACID, A-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-2,3-DIHYDRO-;1H-INDENE-2-ACETIC ACID,α-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-2,3-DIHYDRO-

Suppliers and Price of TERT-BUTOXYCARBONYLAMINO-INDAN-2-YL-ACETIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of TERT-BUTOXYCARBONYLAMINO-INDAN-2-YL-ACETIC ACID

Chemical Property:

Boiling Point:470.9±28.0 °C(Predicted)
PKA:3.91±0.10(Predicted)
PSA：75.63000
Density:1.195±0.06 g/cm3(Predicted)
LogP:2.77020

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of TERT-BUTOXYCARBONYLAMINO-INDAN-2-YL-ACETIC ACID

There total 7 articles about TERT-BUTOXYCARBONYLAMINO-INDAN-2-YL-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 181227-46-3,155239-51-3,16655-71-3
(2R)-amino(2,3-dihydro-1H-inden-2-yl)ethanoic acid

: 181227-48-5,155172-73-9,181227-47-4
(2R)-[(t-butoxycarbonyl)amino](2,3-dihydro-1H-inden-2-yl)ethanoic acid

Guidance literature:: With water; triethylamine; In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1021/jm050557v

Reference yield:

: 216222-68-3
rac-indanylglycine hydantoin

: 181227-48-5,155172-73-9,181227-47-4
(2R)-[(t-butoxycarbonyl)amino](2,3-dihydro-1H-inden-2-yl)ethanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: disodium tetraborate decahydrate; aq. NaOH; D-hydantoinase / dimethylsulfoxide / 45 h / 45 °C / pH 10.5

2: 73.8 g / disodium tetraborate decahydrate; aq. HCl; D-carbamoylase / air / dimethylsulfoxide / 36 h / 45 °C / pH 8.02

3: 96 percent / Et₃N; H₂O / tetrahydrofuran / 16 h / 20 °C

With hydrogenchloride; Sodium borate; sodium hydroxide; D-carbamoylase; D-hydantoinase; water; triethylamine; air; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/jm050557v

Reference yield:

: 870151-49-8
(R)-N-carbamylindanylglycine

: 181227-48-5,155172-73-9,181227-47-4
(2R)-[(t-butoxycarbonyl)amino](2,3-dihydro-1H-inden-2-yl)ethanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 73.8 g / disodium tetraborate decahydrate; aq. HCl; D-carbamoylase / air / dimethylsulfoxide / 36 h / 45 °C / pH 8.02

2: 96 percent / Et₃N; H₂O / tetrahydrofuran / 16 h / 20 °C

With hydrogenchloride; Sodium borate; D-carbamoylase; water; triethylamine; air; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/jm050557v