4-CHLORO-D-TRYPTOPHAN

Base Information

Chemical Name:4-CHLORO-D-TRYPTOPHAN
CAS No.:27542-41-2
Molecular Formula:C₁₁H₁₁ClN₂O₂
Molecular Weight:238.674
Hs Code.:2933998090
Mol file:27542-41-2.mol

Synonyms:4-CHLORO-D-TRYPTOPHAN;D-Tryptophan, 4-chloro-

Suppliers and Price of 4-CHLORO-D-TRYPTOPHAN

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
D-TRYPTOPHAN, 4-CHLORO- 95.00%
5MG
$ 498.61

Activate Scientific
4-Chloro-D-tryptophan 95+% ee
250 mg
$ 279.00

Activate Scientific
4-Chloro-D-tryptophan 95+% ee
5 g
$ 1566.00

Activate Scientific
4-Chloro-D-tryptophan 95+% ee
1 g
$ 581.00

Acrotein
4-Chloro-D-tryptophan 97%
1g
$ 412.50

Total 6 raw suppliers

Chemical Property of 4-CHLORO-D-TRYPTOPHAN

Chemical Property:

Boiling Point:476.9±45.0 °C(Predicted)
PKA:2.19±0.10(Predicted)
PSA：79.11000
Density:1.474±0.06 g/cm3(Predicted)
LogP:2.47600

Purity/Quality:

>98% ^*data from raw suppliers

D-TRYPTOPHAN, 4-CHLORO- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-CHLORO-D-TRYPTOPHAN

There total 23 articles about 4-CHLORO-D-TRYPTOPHAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83-42-1
6-chloro-2-nitrotoluene

: 118244-93-2,27542-41-2,52448-14-3
4-chloro-DL-tryptophan

Guidance literature:: Multi-step reaction with 6 steps

1: DMSO, TritonB / methanol

2: H₂ / 5percent Pd-C / ethyl acetate

3: 80 percent / RuCl₂(PPh₃)3 / toluene / Heating

4: 82 percent / AcOH

5: 87 percent / P(C₄H₉)3 / Heating

6: 1) 10percent NaOH, 2) HS(CH₂)2SO₃H / 1) reflux, 7 h, 2) 110 deg C, 16 h

With 2-Mercaptoethanesulfonic acid; sodium hydroxide; P(C₄H₉)3; hydrogen; N-benzyl-trimethylammonium hydroxide; acetic acid; dimethyl sulfoxide; palladium on activated charcoal; tris(triphenylphosphine)ruthenium(II) chloride; In methanol; ethyl acetate; toluene;
DOI:10.1016/S0040-4039(00)77491-0

Reference yield:

: 102493-68-5
2-(2-chloro-6-nitrophenyl)-ethanol

: 118244-93-2,27542-41-2,52448-14-3
4-chloro-DL-tryptophan

Guidance literature:: Multi-step reaction with 5 steps

1: H₂ / 5percent Pd-C / ethyl acetate

2: 80 percent / RuCl₂(PPh₃)3 / toluene / Heating

3: 82 percent / AcOH

4: 87 percent / P(C₄H₉)3 / Heating

5: 1) 10percent NaOH, 2) HS(CH₂)2SO₃H / 1) reflux, 7 h, 2) 110 deg C, 16 h

With 2-Mercaptoethanesulfonic acid; sodium hydroxide; P(C₄H₉)3; hydrogen; acetic acid; palladium on activated charcoal; tris(triphenylphosphine)ruthenium(II) chloride; In ethyl acetate; toluene;
DOI:10.1016/S0040-4039(00)77491-0

Reference yield:

: 100376-53-2
2-(2-amino-6-chlorophenyl)ethyl alcohol

: 118244-93-2,27542-41-2,52448-14-3
4-chloro-DL-tryptophan

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / RuCl₂(PPh₃)3 / toluene / Heating

2: 82 percent / AcOH

3: 87 percent / P(C₄H₉)3 / Heating

4: 1) 10percent NaOH, 2) HS(CH₂)2SO₃H / 1) reflux, 7 h, 2) 110 deg C, 16 h

With 2-Mercaptoethanesulfonic acid; sodium hydroxide; P(C₄H₉)3; acetic acid; tris(triphenylphosphine)ruthenium(II) chloride; In toluene;
DOI:10.1016/S0040-4039(00)77491-0