100376-53-2

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-AMINO-6-CHLOROPHENYL)ETHAN-1-OL is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs and medications.
Used in Agricultural Industry:
In agriculture, 2-(2-AMINO-6-CHLOROPHENYL)ETHAN-1-OL is used as a precursor in the production of agrochemicals. Its potential applications in this field include the development of new pesticides, herbicides, and other crop protection agents.
Used in Materials Science:
2-(2-AMINO-6-CHLOROPHENYL)ETHAN-1-OL is utilized in materials science for the synthesis of novel materials with unique properties. Its potential applications in this field include the development of advanced polymers, coatings, and other materials with specific characteristics.
Used in Research Applications:
In research, 2-(2-AMINO-6-CHLOROPHENYL)ETHAN-1-OL is employed as a reagent or starting material for various chemical reactions and experiments. Its unique chemical properties make it a valuable tool for studying the synthesis and properties of new organic compounds.

InChI:InChI=1/C8H10ClNO/c9-7-2-1-3-8(10)6(7)4-5-11/h1-3,11H,4-5,10H2

Upstream product

• 97522-09-3 methyl 2-(2-chloro-6-nitrophenyl)acetate 
• 50-00-0 formaldehyd 
• 83-42-1 6-chloro-2-nitrotoluene 
• 102493-68-5 2-(2-chloro-6-nitrophenyl)-ethanol 
• 56433-01-3 2-chloro-6-nitrobenzyl bromide 
• 7439-89-6 iron 
• 31912-08-0 (2-chloro-6-nitro-phenyl)-acetic acid 
• 89277-98-5 2-(2-chloro-6-nitrophenyl)acetonitrile 

Downstream Products

• 20870-77-3 4-chloroindolin-2-one 
• 27542-41-2 4-chloro-D-tryptophan 
• 27542-41-2 (S)-2-amino-3-(4-chloro-1H-indol-3-yl)propanoic acid 
• 118244-93-2 4-chloro-DL-tryptophan 
• 102493-80-1 N-benzyl-4-chloro-5-(2-nitrobuten-1-yl)-2,3-dihydroindole 
• 102493-72-1 N-benzyl-4-chloro-5-(2-nitropropen-1-yl)-2,3-dihydroindole 
• 102493-81-2 1-(1-Benzyl-4-chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propylamine 
• 102493-73-2 2-(1-Benzyl-4-chloro-2,3-dihydro-1H-indol-5-yl)-1-methyl-ethylamine 
• 102493-71-0 N-benzyl-4-chloro-2,3-dihydroindole-5-carboxaldehyde 
• 102493-70-9 N-benzyl-4-chloro-2,3-dihydroindole 
• 41910-64-9 4-chloroindoline 
• 25235-85-2 4-chloro-1H-indole 

Relevant academic research and scientific papers

L-4-Chlorotryptophan from Immature Seeds of Pisum sativum and Reassignment of the Absolute Stereochemistry of N-Malonyl-4-chlorotryptophan

Free 4-chlorotryptophan (4-Cl-Trp) was isolated from immature seeds of P. sativum, identified, and its stereochemistry determined to be L-form.Reinvestigation of the N-malonyl-4-Cl-Trp isolated from the same seeds showed that the stereochemistry of the 4-Cl-Trp residue is L-form.

Ruthenium Catalysed N-Heterocyclisation: Indoles from 2-Aminophenethyl Alcohols

Dichlorotris(triphenylphosphine)ruthenium is highly active as a catalyst for the N-heterocyclisation of 2-aminophenethyl alcohols (2a-d) into indole derivatives in toluene under reflux, and the reactions proceed with spontaneous hydrogen evolution.

Dehydrogenative and Redox-Neutral N-Heterocyclization of Aminoalcohols Catalyzed by Manganese Pincer Complexes

A new manganese catalyzed heterocyclization of aminoalcohols has been accomplished. A wide range of heterocycles were synthesized, including 1,2,3,4-tetrahydroquinolines, dihydroquinolinones, and 2,3,4,5-tetrahydro-1H-benzo[b]azepines. The reaction is performed under mild reaction conditions using air and moisture stable manganese catalysts. The desired heterocycles were obtained in good to excellent yields.

Tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same

A tricyclic compound represented by the general formula (1) and salts thereof. STR1 A method for producing the tricyclic compound and salts thereof, and an antimicrobial agent containing the tricyclic compound and salts thereof as an active ingredient are

Ruthenium-Catalyzed Dehydrogenative N-Heterocyclization: Indoles from 2-Aminophenethyl Alcohols and 2-Nitrophenethyl Alcohols

Indole derivatives 3 were readily obtained from 2-aminophenethyl alcohols 1 in the presence of 2 mol percent (based on 1) of RuCl2(PPh3)3 under reflux in toluene.Indole (3a) was afforded from 2-aminophenethyl alcohol (1a) quantitatively.Other indoles (3) were also obtained in 73-99percent isolated yields from the corresponding 1, which were easily prepared by condensation between the corresponding 2-nitrotoluenes and aldehydes followed by reduction.During the reaction, a stoichiometric amount of hydrogen was spontaneously evolved into the gas phase.With a heterogeneous and homogeneous binary catalyst system, indoles were afforded in one pot from 2-nitrophenethyl alcohols 2 under a hydrogen atmosphere.