3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one

Base Information

Chemical Name:3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one
CAS No.:1016641-53-4
Molecular Formula:C14H18BNO4
Molecular Weight:275.11
Hs Code.:
Mol file:1016641-53-4.mol

Synonyms:benzo[d]oxazol-2(3H);3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2-one;2(3H)-Benzoxazolone, 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2(3H)-one

Suppliers and Price of 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
1g
$ 314.00

Chemenu
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
250mg
$ 119.00

Chemenu
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
1g
$ 317.00

Chemenu
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
100mg
$ 84.00

Chemenu
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
5g
$ 950.00

Ambeed
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
5g
$ 1073.00

Ambeed
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
1g
$ 357.00

Ambeed
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
250mg
$ 133.00

Ambeed
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98%
100mg
$ 88.00

Total 9 raw suppliers

Chemical Property of 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one

Chemical Property:

Boiling Point:390.4±44.0 °C(Predicted)
PKA:-0.96±0.20(Predicted)
PSA：53.60000
Density:1.20±0.1 g/cm3(Predicted)
LogP:1.43070
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one

There total 2 articles about 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 67927-44-0
6-bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one

: 73183-34-3
bis(pinacol)diborane

: 1016641-53-4
3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2(3H)-one

Guidance literature:: With potassium acetate; trans-bis(triphenylphosphine)palladium dichloride; In 1,4-dioxane; at 100 ℃; for 7h;

Reference yield:

: 19932-85-5
6-bromobenzo[d]oxazol-2(3H)-one

: 1016641-53-4
3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 3 h / 80 °C

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane; dichloromethane / 90 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; potassium carbonate; In 1,4-dioxane; dichloromethane; acetone;

Reference yield:

: 1016641-53-4
3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2(3H)-one

: 4-(5-chloro-8-{[(3R)-1-(2-cyanoethyl)piperidin-3-yl]methoxy}imidazo[1,2-a]pyrazin-6-yl)benzonitrile

: 76-05-1
trifluoroacetic acid

: 4-[8-{[(3R)-1-(2-cyanoethyl)piperidin-3-yl]methoxy}-5-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)imidazo[1,2-a]pyrazin-6-yl]benzonitrile trifluoroacetate

Guidance literature:: 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2(3H)-one; 4-(5-chloro-8-{[(3R)-1-(2-cyanoethyl)piperidin-3-yl]methoxy}imidazo[1,2-a]pyrazin-6-yl)benzonitrile; With potassium phosphate; [1,1′-bis(di-cyclohexylphosphino)ferrocene]dichloropalladium(II); In 1,4-dioxane; water; at 90 ℃; for 2h; Sealed tube;

trifluoroacetic acid; In water; acetonitrile; pH=2;