N-4-Piperidylacetanilide Hydrochloride

Base Information

• Chemical Name: N-4-Piperidylacetanilide Hydrochloride
• CAS No.: 22352-82-5
• Molecular Formula: C13H19ClN2O
• Molecular Weight: 254.76
• Mol file: 22352-82-5.mol

Synonyms:N-4-Piperidylacetanilide Hydrochloride

Chemical Property of N-4-Piperidylacetanilide Hydrochloride

Chemical Property:

• PSA: 32.34000
• LogP: 2.92230

Purity/Quality:

99% ^*data from raw suppliers

N-4-Piperidylacetanilide Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Acetyl norfentanyl (hydrochloride) (Item No. ISO00130) is an analytical reference material that is structurally similar to known opioids. It is a metabolite of acetyl fentanyl (Item Nos. ISO00128 | ISO60128).This product is intended for research and forensic applications.
• Uses: N-4-Piperidylacetanilide is an metabolite of Acetyl Fentanyl (A175000), an analogue of fentanyl analog.

Technology Process of N-4-Piperidylacetanilide Hydrochloride

There total 2 articles about N-4-Piperidylacetanilide Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-<1-(2-Phenylethyl)-4-piperidyl>-N-phenylacetamide Hydrochloride (117332-89-5) → N-phenyl-N-(piperidin-4-yl)acetamide hydrochloride (22352-82-5)

Guidance literature:

With NADPH; cytochrome P₄₅₀; In aq. phosphate buffer; ethanol; acetonitrile; at 20 ℃; pH=7.4; Enzymatic reaction;

DOI:10.1021/ac4036197

Reference yield:

→ N-phenyl-N-(piperidin-4-yl)acetamide hydrochloride (22352-82-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 25 ℃; for 16h;

Reference yield: 58.0%

N-phenyl-N-(piperidin-4-yl)acetamide hydrochloride (22352-82-5) + 1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → β-hydroxy-acetylfentanyl (1453-59-4)

Guidance literature:

With sodium hydrogencarbonate; In water; butanone; at 90 ℃; for 6h;

DOI:10.1248/bpb.b17-00709

upstream raw materials:

N-<1-(2-Phenylethyl)-4-piperidyl>-N-phenylacetamide Hydrochloride

Downstream raw materials:

β-hydroxy-acetylfentanyl

Refernces

• 1、 -. "MUSCARINIC AGONISTS". Page/Page column 44; 45; 80. . Retrieved 2017/02/28.