(1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE

Base Information

Chemical Name:(1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE
CAS No.:1027343-55-0
Molecular Formula:C₁₅H₂₃NO₃
Molecular Weight:265.353
Hs Code.:2914290090
Mol file:1027343-55-0.mol

Synonyms:(1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE

Suppliers and Price of (1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(1R,2R,5S,7R)-N-tert-Butoxycarbonyl-8,8-dimethyl-3-azatricyclo[5.1.1.0^2,5]nonan-4-one
100 mg
$ 496.00

Apolloscientific
(1R,2R,5S,7R)-N-tert-Butoxycarbonyl-8,8-dimethyl-3-azatricyclo[5.1.1.0^2,5]nonan-4-one
100mg
$ 419.00

American Custom Chemicals Corporation
(1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE 95.00%
100MG
$ 826.35

American Custom Chemicals Corporation
(1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE 95.00%
5MG
$ 498.12

Total 3 raw suppliers

Chemical Property of (1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE

Chemical Property:

PSA：46.61000
LogP:2.75240

Purity/Quality:

97% ^*data from raw suppliers

(1R,2R,5S,7R)-N-tert-Butoxycarbonyl-8,8-dimethyl-3-azatricyclo[5.1.1.0^2,5]nonan-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE

There total 2 articles about (1R,2R,5S,7R)-N-TERT-BUTOXYCARBONYL-8,8-DIMETHYL-3-AZATRICYCLO[5.1.1.0(2,5)]NONAN-4-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1027343-54-9
(1R,2R,5S,7R)-8,8-dimethyl-3-azatricyclo[5.1.1.0(2,5)]nonan-4-one

: 24424-99-5
di-tert-butyl dicarbonate

: 1027343-55-0
(1R,2R,5S,7R)-N-tert-butoxycarbonyl-8,8-dimethyl-3-azatricyclo[5.1.1.0(2,5)]nonan-4-one

Guidance literature:: With triethylamine; dmap; In tetrahydrofuran; at 20 ℃; for 6h;

Reference yield:

: 23978-82-7
(1S,5R)-6,6-dimethylbicyclo<3.1.1>hept-2-ene

: 1027343-55-0
(1R,2R,5S,7R)-N-tert-butoxycarbonyl-8,8-dimethyl-3-azatricyclo[5.1.1.0(2,5)]nonan-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 168 h / 20 °C

2: triethylamine; dmap / tetrahydrofuran / 6 h / 20 °C

With dmap; triethylamine; In tetrahydrofuran; diethyl ether;
DOI:10.1016/j.tetasy.2013.04.003

Reference yield:

: 1027343-55-0
(1R,2R,5S,7R)-N-tert-butoxycarbonyl-8,8-dimethyl-3-azatricyclo[5.1.1.0(2,5)]nonan-4-one

: 1438844-84-8
(1R,2R,3S,5R)-2-(N-benzyl-4-methylphenylsulfonamido)-N,N,6,6-tetramethylbicyclo[3.1.1]heptane-3-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: diethyl ether; water / 24 h / 20 °C

2.1: water; hydrogenchloride / diethyl ether / 24 h / 20 °C

3.1: ethanol / 2 h / 20 °C

3.2: 24 h / 20 °C

4.1: triethylamine; dmap / chloroform / 20 h / 0 °C / Reflux

With hydrogenchloride; dmap; water; triethylamine; In diethyl ether; ethanol; chloroform; water;
DOI:10.1016/j.tetasy.2013.04.003