1-Cyclohexyl-1-pentanol

Base Information

• Chemical Name: 1-Cyclohexyl-1-pentanol
• CAS No.: 93548-33-5
• Molecular Formula: C11H22O
• Molecular Weight: 170.295
• European Community (EC) Number: 663-321-0
• DSSTox Substance ID: DTXSID50918348
• Nikkaji Number: J1.083.134B
• Mol file: 93548-33-5.mol

Synonyms:1-Cyclohexyl-1-pentanol;7338-43-4;1-cyclohexylpentan-1-ol;93548-33-5;cyclohexylpentanol-1;1-cyclohexyl-pentan-1-ol;Cyclohexanemethanol,a-butyl-;(1-Hydroxypentyl)cyclohexane;SCHEMBL3155145;PKXSPCMDZCKLCI-UHFFFAOYSA-;DTXSID50918348;PKXSPCMDZCKLCI-UHFFFAOYSA-N;MFCD00045483;AKOS009158342;(-)-1-CYCLOHEXYL-1-PENTANOL;CS-0358146;FT-0636442;InChI=1/C11H22O/c1-2-3-9-11(12)10-7-5-4-6-8-10/h10-12H,2-9H2,1H3

Chemical Property of 1-Cyclohexyl-1-pentanol

Chemical Property:

• Boiling Point: 243.2°Cat760mmHg
• Flash Point: 107.9°C
• Density: 0.9g/cm³
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 170.167065321
• Heavy Atom Count: 12
• Complexity: 106

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCC(C1CCCCC1)O

Technology Process of 1-Cyclohexyl-1-pentanol

There total 42 articles about 1-Cyclohexyl-1-pentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

n-butyl magnesium bromide (693-03-8) + cyclohexanecarbaldehyde (2043-61-0) → (+/-)-1-cyclohexyl-1-pentanol (63126-49-8,93548-33-5,114376-32-8,7338-43-4)

Guidance literature:

n-butyl magnesium bromide; With manganese(ll) chloride; In tetrahydrofuran; at 0 ℃; for 0.333333h;

cyclohexanecarbaldehyde; In tetrahydrofuran; at -78 ℃; for 0.333333h;

DOI:10.1246/bcsj.70.2297

Reference yield: 97.0%

n-butyl magnesium bromide (693-03-8) + cyclohexanecarbaldehyde (2043-61-0) → 1-Cyclohexyl-2-(trimethylsilyl)ethanol (55629-30-6) + (+/-)-1-cyclohexyl-1-pentanol (63126-49-8,93548-33-5,114376-32-8,7338-43-4)

Guidance literature:

n-butyl magnesium bromide; Me₃SiCH₂MgX; With manganese(ll) chloride; In tetrahydrofuran; at 0 ℃; for 0.333333h;

cyclohexanecarbaldehyde; In tetrahydrofuran; at -78 ℃; for 0.333333h;

DOI:10.1246/bcsj.70.2297

Reference yield: 97.0%

n-butyl magnesium bromide (693-03-8) + cyclohexanecarbaldehyde (2043-61-0) → (S)-(-)-1-cyclohexylpentanol (93548-33-5)

Guidance literature:

n-butyl magnesium bromide; With titanium(IV) isopropylate; (Sa)-2'-[(R)-hydroxy(pyridin-4-yl)methyl]-(1,1'-binaphthalen)-2-ol; In diethyl ether; at -20 ℃; for 0.25h; Schlenk technique; Inert atmosphere;

cyclohexanecarbaldehyde; In diethyl ether; at -20 ℃; for 3h; Reagent/catalyst; Temperature; Solvent; enantioselective reaction;

DOI:10.1002/adsc.201201117

upstream raw materials:

pentanal

cyclohexylmagnesium bromide

(2R,4R)-4-(1-Cyclohexyl-pentyloxy)-pentan-2-ol

(1S,1'R,3'R)-1-cyclohexyl-1-(3'-hydroxy-1'-methylbutoxy)pentane

Downstream raw materials:

C₁₃H₂₄O₂

(R)-(+)-1-cyclohexylpentanol

1-cyclohexyl-1-pentanone