3-(tert-butyldiMethylsilanyloxyMethyl)-4-chlorobenzylaMine

Base Information Edit

Chemical Name:3-(tert-butyldiMethylsilanyloxyMethyl)-4-chlorobenzylaMine
CAS No.:946000-12-0
Molecular Formula:C14H24ClNOSi
Molecular Weight:285.889
Hs Code.:
Mol file:946000-12-0.mol

Synonyms:3-(tert-butyldiMethylsilanyloxyMethyl)-4-chlorobenzylaMine

Suppliers and Price of 3-(tert-butyldiMethylsilanyloxyMethyl)-4-chlorobenzylaMine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(3-(((tert-Butyldimethylsilyl)oxy)methyl)-4-chlorophenyl)methanamine 97%
250mg
$ 272.00

Crysdot
(3-(((tert-Butyldimethylsilyl)oxy)methyl)-4-chlorophenyl)methanamine 97%
1g
$ 680.00

Chemenu
(3-(((tert-Butyldimethylsilyl)oxy)methyl)-4-chlorophenyl)methanamine 97%
1g
$ 636.00

Total 2 raw suppliers

Chemical Property of 3-(tert-butyldiMethylsilanyloxyMethyl)-4-chlorobenzylaMine Edit

Chemical Property:

Boiling Point:337.6±32.0 °C (760 mmHg)
PSA：35.25000
Density:1.025±0.06 g/cm3 (20 °C, 760 mmHg)
LogP:5.02080

Purity/Quality:

≥95% ^*data from raw suppliers

(3-(((tert-Butyldimethylsilyl)oxy)methyl)-4-chlorophenyl)methanamine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(tert-butyldiMethylsilanyloxyMethyl)-4-chlorobenzylaMine

There total 4 articles about 3-(tert-butyldiMethylsilanyloxyMethyl)-4-chlorobenzylaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 946000-10-8
3-(tert-butyl-dimethyl-silanyloxymethyl)-4-chloro-benzaldehyde oxime

: 946000-12-0
3-(tert-butyl-dimethyl-silanyloxymethyl)-4-chloro-benzylamine

Guidance literature:: 3-(tert-butyl-dimethyl-silanyloxymethyl)-4-chloro-benzaldehyde oxime; With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 1h;

With Rochelle's salt; In diethyl ether; for 3h;

Reference yield:

: 873782-26-4
((5-bromo-2-chlorobenzyl)oxy)(tert-butyl)dimethylsilane

: 946000-12-0
3-(tert-butyl-dimethyl-silanyloxymethyl)-4-chloro-benzylamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: -78 - 20 °C

2.1: sodium hydrogencarbonate / acetonitrile / 0.08 h

2.2: 0.17 h

3.1: lithium aluminium tetrahydride / diethyl ether / 1 h / 20 °C

3.2: 3 h

With lithium aluminium tetrahydride; n-butyllithium; sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; hexane; acetonitrile;

Reference yield:

: 946000-08-4
3-(((tert-butyldimethylsilyl)oxy)methyl)-4-chlorobenzaldehyde

: 946000-12-0
3-(tert-butyl-dimethyl-silanyloxymethyl)-4-chloro-benzylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / acetonitrile / 0.08 h

1.2: 0.17 h

2.1: lithium aluminium tetrahydride / diethyl ether / 1 h / 20 °C

2.2: 3 h

With lithium aluminium tetrahydride; sodium hydrogencarbonate; In diethyl ether; acetonitrile;