LEUKOTRIENE B4, METHYL ESTER

Base Information

Chemical Name:LEUKOTRIENE B4, METHYL ESTER
CAS No.:83058-42-8
Molecular Formula:C₂₁H₃₄O₄
Molecular Weight:350.499
Hs Code.:

Synonyms:LEUKOTRIENE B4, METHYL ESTER

Suppliers and Price of LEUKOTRIENE B4, METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of LEUKOTRIENE B4, METHYL ESTER

Chemical Property:

PSA：66.76000
LogP:4.24670
Storage Temp.:-20°C

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F,T
Statements: 11
Safety Statements: 7-16-23-45

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of LEUKOTRIENE B4, METHYL ESTER

There total 92 articles about LEUKOTRIENE B4, METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 90108-36-4
(5S,6Z,8E,10E,12R,14Z)-methyl 5,12-bis<(tert-butyldiphenylsilyl)oxy>-6,8,10,14-eicosatetraenoate

: 83058-42-8
Methyl (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxyeicosa-6,8,10,14-tetraenoate

Guidance literature:: With pyridine; hydrogen fluoride; tetrabutyl ammonium fluoride; In tetrahydrofuran; at 30 ℃; for 24h;
DOI:10.1021/jo00065a012

Reference yield: 70.0%

: 136693-12-4
(-)-(8E,10E,14Z)-(5S,12R)-methyl 5,12-dihydroxy-8,10,14-eicosatrien-6-ynoate

: 83058-42-8
Methyl (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxyeicosa-6,8,10,14-tetraenoate

Guidance literature:: With zinc; In methanol; at 35 ℃; for 15h;
DOI:10.1016/S0040-4020(01)88516-1

Reference yield:

: 90108-28-4
(5S)-5-hydroxy-hept-6-ynoic acid, methyl ester

: 83058-42-8
Methyl (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxyeicosa-6,8,10,14-tetraenoate

Guidance literature:: Multi-step reaction with 5 steps

1: 95 percent / imidazole / dimethylformamide / 35 °C

2: 78 percent / n-butylamine, copper iodide / Pd3)>4 / benzene / 3 h / Ambient temperature

3: Bu₄NF / tetrahydrofuran / 2 h / Ambient temperature

4: 85 percent

5: 65 percent / Zn, MeOH / H₂O / 5 h / 30 °C

With 1H-imidazole; methanol; copper(l) iodide; tetrabutyl ammonium fluoride; N-butylamine; zinc; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo00037a044