3-Hydroxy-1-naphthaldehyde

Base Information

• Chemical Name: 3-Hydroxy-1-naphthaldehyde
• CAS No.: 91136-43-5
• Molecular Formula: C₁₁H₈O₂
• Molecular Weight: 172.183
• European Community (EC) Number: 869-550-4
• DSSTox Substance ID: DTXSID00529923
• Wikidata: Q82400691
• Mol file: 91136-43-5.mol

Synonyms:3-Hydroxy-1-naphthaldehyde;91136-43-5;3-hydroxynaphthalene-1-carbaldehyde;3-Hydroxynaphthalene-1-carboxaldehyde;MFCD17012437;b-hydroxy-naphthaldehyde;SCHEMBL3268303;DTXSID00529923;PLCQXZXTFCITAJ-UHFFFAOYSA-N;AKOS022638442;AS-31873;SY028399;CS-0163730;EN300-1602398;A860593;Z1255367545

Chemical Property of 3-Hydroxy-1-naphthaldehyde

Chemical Property:

• PSA: 37.30000
• LogP: 2.35790
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 172.052429494
• Heavy Atom Count: 13
• Complexity: 191

Purity/Quality:

97% ^*data from raw suppliers

3-HYDROXY-1-NAPHTHALDEHYDE 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=C(C=C2C=O)O

Technology Process of 3-Hydroxy-1-naphthaldehyde

There total 2 articles about 3-Hydroxy-1-naphthaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-naphthalen-2-ol (5498-31-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3-hydroxynaphthalenecarboxaldehyde (91136-43-5)

Guidance literature:

4-bromo-naphthalen-2-ol; With n-butyllithium; sodium hydride;

N,N-dimethyl-formamide;

DOI:10.1021/jm3012189

Reference yield:

N-Formylpiperidine (2591-86-8) + 4-bromo-naphthalen-2-ol (5498-31-7) → 3-hydroxynaphthalenecarboxaldehyde (91136-43-5)

Guidance literature:

Yield given; Multistep reaction;

DOI:10.1016/S0040-4020(99)00245-8

Reference yield: 46.0%

1,1-diphenyl-2-propyn-1-ol (3923-52-2) + 3-hydroxynaphthalenecarboxaldehyde (91136-43-5) → 3,3-diphenyl-6-formyl-<3H>-naphtho<2,1-b>pyran (227471-73-0)

Guidance literature:

With toluene-4-sulfonic acid; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4020(99)00245-8

upstream raw materials:

N-Formylpiperidine

4-bromo-naphthalen-2-ol

N,N-dimethyl-formamide

Downstream raw materials:

3,3-diphenyl-6-formyl-<3H>-naphtho<2,1-b>pyran