1-Cyclopropyl-1H-pyrazole

Base Information

Chemical Name:1-Cyclopropyl-1H-pyrazole
CAS No.:1151814-36-6
Molecular Formula:C6H8N2
Molecular Weight:108.14112
Hs Code.:2933199090
Mol file:1151814-36-6.mol

Synonyms:1-Cyclopropyl-1H-pyrazole

Suppliers and Price of 1-Cyclopropyl-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Cyclopropyl-1H-pyrazole
1g
$ 1340.00

SynQuest Laboratories
1-Cyclopropyl-1H-pyrazole 95%
250 mg
$ 320.00

SynQuest Laboratories
1-Cyclopropyl-1H-pyrazole 95%
1 g
$ 808.00

Crysdot
1-Cyclopropyl-1H-pyrazole 95+%
25g
$ 3465.00

Crysdot
1-Cyclopropyl-1H-pyrazole 95+%
10g
$ 1733.00

Crysdot
1-Cyclopropyl-1H-pyrazole 95+%
5g
$ 1010.00

Crysdot
1-Cyclopropyl-1H-pyrazole 95+%
1g
$ 347.00

Chemenu
1-Cyclopropylpyrazole 95+%
1g
$ 623.00

Chemenu
1-Cyclopropylpyrazole 95+%
100mg
$ 187.00

Apolloscientific
1-Cyclopropyl-1H-pyrazole 95%
250mg
$ 200.00

Total 18 raw suppliers

Chemical Property of 1-Cyclopropyl-1H-pyrazole

Chemical Property:

Boiling Point:189.7±9.0 °C(Predicted)
PKA:3.46±0.12(Predicted)
PSA：17.82000
Density:1.23±0.1 g/cm3(Predicted)
LogP:1.21800
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1-Cyclopropyl-1H-pyrazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-Cyclopropyl-1H-pyrazole is used in the preparation of therapeutic agents for malignant lymphoma. It is used in the preparation of various specific tyrosine kinase inhibitors.

Technology Process of 1-Cyclopropyl-1H-pyrazole

There total 2 articles about 1-Cyclopropyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1378847-65-4
cyclopropylhydrazine oxalate

: 927-63-9
3-dimethylaminoacrolein

: 1151814-36-6
1-cyclopropylpyrazole

Guidance literature:: With sodium acetate; In ethanol; at 70 ℃; for 16h;

Reference yield:

: 288-13-1
NH-pyrazole

: 411235-57-9
cyclopropylboronic acid

: 1151814-36-6
1-cyclopropylpyrazole

Guidance literature:: With [2,2]bipyridinyl; copper diacetate; sodium carbonate; In 1,2-dichloro-ethane; at 70 ℃; for 4h;

Reference yield:

: 1151814-36-6
1-cyclopropylpyrazole

: 1151802-22-0
1-cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / chloroform / 1 h / 20 °C

2: sodium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide / 1 h / 150 °C / Inert atmosphere; Sealed microwave vial

With bromine; sodium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In chloroform; N,N-dimethyl-formamide;