Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI)

Base Information

Chemical Name:Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI)
CAS No.:120966-82-7
Molecular Formula:C6H11NO
Molecular Weight:113.15764
Hs Code.:
Mol file:120966-82-7.mol

Synonyms:Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI);L-Pro Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI);(S)-2-Acetyl-pyrrolidine;(S)-1-(pyrrolidin-2-yl)ethanone

Suppliers and Price of Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
(S)-2-Acetyl-pyrrolidine 97%
250mg
$ 225.00

Total 6 raw suppliers

Chemical Property of Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI)

Chemical Property:

PSA：29.10000
LogP:0.65620

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-Acetyl-pyrrolidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI)

There total 2 articles about Ethanone, 1-(2-pyrrolidinyl)-, (S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91550-08-2
(S)-2-acetylpyrrolidine-1-carboxylic acid tert-butyl ester

: 120966-82-7,60026-20-2
L(-)-proline

Guidance literature:: With trifluoroacetic acid;
DOI:10.1016/j.bmcl.2004.08.057

Reference yield:

: 115186-37-3
tert-butyl (2S)-2-{[N-methoxy(N-methyl)amino]carbonyl}pyrrolidine-1-carboxylate

: 120966-82-7,60026-20-2
L(-)-proline

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / -78 - -40 °C

2: TFA

With trifluoroacetic acid; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2004.08.057

Reference yield:

: 120966-82-7,60026-20-2
L(-)-proline

: 473797-83-0
isophthalic acid mono(L-prolyl-pyrrolidine) amide

: isophthalic acid 2(S)-acetylpyrrolidine L-prolyl-pyrrolidine amide

Guidance literature:: isophthalic acid mono(L-prolyl-pyrrolidine) amide; With pivaloyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 1h;

L(-)-proline; With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1021/jm030811o