91550-08-2

Basic information

• Product Name: (S)-1-Boc-2-acetyl-pyrrolidine
• Synonyms: (S)-1-Boc-2-acetyl-pyrrolidine;(S)-2-acetylpyrrolidine-1-carboxylic acid tert-butyl ester;tert-butyl (S)-2-formylpyrrolidine-1-carboxylate;(S)-tert-Butyl 2-acetylpyrrolidine-1-carboxylate;tert-butyl (2S)-2-acetylpyrrolidine-1-carboxylate
• CAS NO: 91550-08-2
• Molecular Formula: C₁₁H₁₉NO₃
• Molecular Weight: 213.27346
• Mol File: 91550-08-2.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (S)-1-Boc-2-acetyl-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Boc-2-acetyl-pyrrolidine(91550-08-2)
• EPA Substance Registry System: (S)-1-Boc-2-acetyl-pyrrolidine(91550-08-2)

Safety Data

• Hazardous Substances Data: 91550-08-2(Hazardous Substances Data)

Usage

General Description

(S)-1-Boc-2-acetyl-pyrrolidine, also known as (S)-2-acetyl-1-(tert-butoxycarbonyl)pyrrolidine, is a chemical compound with the molecular formula C12H19NO3. It is a derivative of pyrrolidine and is commonly used in organic synthesis and pharmaceutical research. (S)-1-Boc-2-acetyl-pyrrolidine is characterized by its chiral nature, with one chiral center, and it is often employed as a chiral building block in the synthesis of various pharmaceutical intermediates. (S)-1-Boc-2-acetyl-pyrrolidine has also been studied for its potential pharmacological properties and biological activities, making it a valuable compound in medicinal chemistry and drug development.

Upstream product

• 33857-76-0 Boc-proline 2-thiopyridyl ester 
• 115186-37-3 tert-butyl (2S)-2-{[N-methoxy(N-methyl)amino]carbonyl}pyrrolidine-1-carboxylate 
• 147-85-3 L-proline 
• 917-54-4 methyllithium 
• 239483-01-3 (S)-2-(methoxymethylcarbamoyl)pyrrolidine-1-carboxylic acid tert-butyl ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 69610-41-9 Boc-L-Pro-H 
• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 75-16-1 methylmagnesium bromide 
• 290327-92-3 tert-butyl-(2S)-2-(1-hydroxyethyl)pyrrolidine-1-carboxylate 
• 141874-26-2 N-Boc-(S)-proline chloride 
• 676-58-4 methylmagnesium chloride 

Downstream Products

• 1071976-38-9 (S)-tert-butyl 2-(4-phenyl-1,2,3-thiadiazol-5-ylcarbamoyl)pyrrolidine-1-carboxylate 

Relevant articles and documents

Macrocyclic compound serving as ALK and ROS regulators

The invention belongs to the field of medicinal chemistry, and relates to a macrocyclic compound serving as an ALK and ROS regulators, in particular to a compound as shown in a formula I or pharmaceutically acceptable salt thereof, a preparation method, a

Studies on Pumiliotoxin A Alkaloids: An Approach to Preparing the Indolizidinic Core by Intramolecular Diastereoselective N-Heterocyclic Carbene Catalyzed Benzoin Reaction

In this article, we describe the development of a convergent organocatalytic strategy to prepare the indolizidinic core of the pumiliotoxin A alkaloid family. The key step of the proposed strategy is based on a diastereoselective N-heterocyclic carbene ca

An intramolecular Tsuji-Trost reaction based approach to the synthesis of 6-methylene indolizidines

Herein we describe the efficient stereoselective preparation of C8 substituted indolizidines bearing a 6-methylene group, from the chiral pool starting material l-proline. This synthesis, employing a Tsuji-Trost reaction as the key step, represents a potentially, efficient route to pumiliotoxin natural product epimers. Crown Copyright