5-Isoxazolepropanoic acid, 3-methyl-4-nitro--alpha--phenyl-

Base Information

Chemical Name:5-Isoxazolepropanoic acid, 3-methyl-4-nitro--alpha--phenyl-
CAS No.:929719-07-3
Molecular Formula:C13H12N2O5
Molecular Weight:276.24
Hs Code.:
Mol file:929719-07-3.mol

Synonyms:5-Isoxazolepropanoic acid, 3-methyl-4-nitro--alpha--phenyl-

Suppliers and Price of 5-Isoxazolepropanoic acid, 3-methyl-4-nitro--alpha--phenyl-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Isoxazolepropanoic acid, 3-methyl-4-nitro--alpha--phenyl-

Chemical Property:

Melting Point:145-146 °C
Boiling Point:428.2±40.0 °C(Predicted)
PKA:3.65±0.10(Predicted)
PSA：109.15000
Density:1.388±0.06 g/cm3(Predicted)
LogP:2.82530

Purity/Quality:

Safty Information:

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Technology Process of 5-Isoxazolepropanoic acid, 3-methyl-4-nitro--alpha--phenyl-

There total 4 articles about 5-Isoxazolepropanoic acid, 3-methyl-4-nitro--alpha--phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 929719-03-9
3-methyl-4-nitro-5-(3-nitro-2-phenylpropyl)isoxazole

: 929719-07-3
3-(3-methyl-4-nitroizoxazol-5-yl)-2-phenylpropionic acid

Guidance literature:: With hydrogenchloride; In ethanol; for 24h; Heating;
DOI:10.1016/j.tet.2006.12.044

Reference yield:

: 1123-49-5
3,5-dimethyl-4-nitroisoxazole

: 929719-07-3
3-(3-methyl-4-nitroizoxazol-5-yl)-2-phenylpropionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: piperidine / ethanol / 2 h / 65 °C

2: piperidine / ethanol / 4 h / 65 °C

3: HCl / ethanol / 24 h / Heating

With piperidine; hydrogenchloride; In ethanol; 1: Knoevenagel reaction / 2: Michael reaction;
DOI:10.1016/j.tet.2006.12.044

Reference yield:

: 51978-94-0,53557-94-1
(E)-3-methyl-4-nitro-5-styrylisoxazole

: 929719-07-3
3-(3-methyl-4-nitroizoxazol-5-yl)-2-phenylpropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine / ethanol / 4 h / 65 °C

2: HCl / ethanol / 24 h / Heating

With piperidine; hydrogenchloride; In ethanol; 1: Michael reaction;
DOI:10.1016/j.tet.2006.12.044