929719-03-9

Basic information

• Product Name: Isoxazole, 3-methyl-4-nitro-5-(3-nitro-2-phenylpropyl)-
• Synonyms: Isoxazole, 3-methyl-4-nitro-5-(3-nitro-2-phenylpropyl)-
• CAS NO: 929719-03-9
• Molecular Formula: C₁₃H₁₃N₃O₅
• Molecular Weight: 291.26
• Mol File: 929719-03-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isoxazole, 3-methyl-4-nitro-5-(3-nitro-2-phenylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazole, 3-methyl-4-nitro-5-(3-nitro-2-phenylpropyl)-(929719-03-9)
• EPA Substance Registry System: Isoxazole, 3-methyl-4-nitro-5-(3-nitro-2-phenylpropyl)-(929719-03-9)

Safety Data

• Hazardous Substances Data: 929719-03-9(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 
• 51978-94-0 (E)-3-methyl-4-nitro-5-styrylisoxazole 
• 100-52-7 benzaldehyde 
• 1123-49-5 3,5-dimethyl-4-nitroisoxazole 

Downstream Products

• 929719-10-8 3-(5-methyl-4-nitro-2H-pyrazol-3-yl)-2-phenylpropionic acid 
• 929719-07-3 3-(3-methyl-4-nitroizoxazol-5-yl)-2-phenylpropionic acid 

Relevant articles and documents

Catalytic asymmetric conjugate addition of nitroalkanes to 4-nitro5-styrylisoxazoles

(Chemical equation presented) Nitro versus nitro: 4-Nitro-5- styrylisoxazoles were used as masked α,β-unsaturated carboxylic acids in the titled catalytic asymmetric transformation. The 4-nitroisoxazole core acts as an activator of the conjugated alkene and a latent carboxylate functionality. The reaction proceeded with 5 mol% of a readily prepared phasetransfer catalyst at room temperature with remarkable diastereo- and enantioselectivity (see scheme).

Modular synthesis of isoxazolopyridones and pyrazolopyridones

Herein we described the preparation of two novel heterocyclic nuclei isoxazolopyridone and pyrazolopyridone. The syntheses are modular in nature and fast to execute. The title compounds were obtained pure without intervention of chromatography.