2-Geranyl-4-isobutyrylphloroglucinol

Base Information

Chemical Name:2-Geranyl-4-isobutyrylphloroglucinol
CAS No.:72008-03-8
Molecular Formula:C₂₀H₂₈O₄
Molecular Weight:332.44
Hs Code.:
Mol file:72008-03-8.mol

Synonyms:2-Geranyl-4-isobutyrylphloroglucinol;3-Geranyl-1-(2'-methylpropanoyl)phloroglucinol;2-Geranyl-4-(2-methylpropanoyl)phloroglucinol

Suppliers and Price of 2-Geranyl-4-isobutyrylphloroglucinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of 2-Geranyl-4-isobutyrylphloroglucinol

Chemical Property:

Boiling Point:491.6±45.0 °C(Predicted)
PKA:7.76±0.50(Predicted)
PSA：77.76000
Density:1.103±0.06 g/cm3(Predicted)
LogP:4.87730

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Geranyl-4-isobutyrylphloroglucinol

There total 3 articles about 2-Geranyl-4-isobutyrylphloroglucinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 6138-90-5
trans-geranyl bromide

: 35458-21-0
phlorisobutyrophenone

: 72008-03-8,72008-05-0
(E)-1-(3-(3,7-dimethylocta-2,6-dien-1-yl)-2,4,6-trihydroxyphenyl)-2-methylpropan-1-one

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1016/j.tet.2011.09.075

Reference yield: 32.85%

: 763-10-0
geranyl diphosphate

: 35458-21-0
phlorisobutyrophenone

: 71539-65-6
1-(4-(E-3,7-dimethylocta-2,6-dienyloxy)-2.6-dihydroxylphenyl)-2-methylpropan-1-one

: 72008-03-8,72008-05-0
(E)-1-(3-(3,7-dimethylocta-2,6-dien-1-yl)-2,4,6-trihydroxyphenyl)-2-methylpropan-1-one

Guidance literature:: With Aspergillus terreus aromatic prenyltransferase; calcium chloride; In dimethyl sulfoxide; glycerol; at 37 ℃; for 2h; pH=7.5; Enzymatic reaction;
DOI:10.1021/acs.orglett.6b03594

Reference yield:

: 108-73-6
3,5-dihydroxyphenol

: 72008-03-8,72008-05-0
(E)-1-(3-(3,7-dimethylocta-2,6-dien-1-yl)-2,4,6-trihydroxyphenyl)-2-methylpropan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / carbon disulfide; nitrobenzene / 1 h / 55 °C

1.2: 1 h / 55 °C

2.1: potassium carbonate / acetone / 24 h / Reflux

With aluminum (III) chloride; potassium carbonate; In carbon disulfide; nitrobenzene; acetone; 1.1: |Friedel-Crafts Acylation;
DOI:10.1016/j.ejmech.2014.08.017