2-Phenylimidazo[2,1-a]phthalazin-6-amine

Base Information

Chemical Name:2-Phenylimidazo[2,1-a]phthalazin-6-amine
CAS No.:54753-08-1
Molecular Formula:C16H12N4
Molecular Weight:260.29
Hs Code.:
DSSTox Substance ID:DTXSID301327987
Nikkaji Number:J534.831E
ChEMBL ID:CHEMBL1425080
Mol file:54753-08-1.mol

Synonyms:2-phenylimidazo[2,1-a]phthalazin-6-amine;2-Phenyl-imidazo[2,1-a]phthalazin-6-ylamine;54753-08-1;MLS001006666;SMR000349646;Enamine_005509;CHEMBL1425080;BDBM95964;cid_3765310;DTXSID301327987;HMS1409K09;HMS2717A07;AKOS034464606;WAY-612616;2-phenyl-6-imidazo[2,1-a]phthalazinamine;CS-0219933;EN300-05360;(2-phenylimidazo[2,1-a]phthalazin-6-yl)amine;SR-01000041284;J-510261;SR-01000041284-1;Z56900779

Suppliers and Price of 2-Phenylimidazo[2,1-a]phthalazin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-PHENYL-IMIDAZO[2,1-A]PHTHALAZIN-6-YLAMINE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
2-PHENYL-IMIDAZO[2,1-A]PHTHALAZIN-6-YLAMINE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
2-PHENYL-IMIDAZO[2,1-A]PHTHALAZIN-6-YLAMINE 95.00%
1G
$ 852.55

Total 6 raw suppliers

Chemical Property of 2-Phenylimidazo[2,1-a]phthalazin-6-amine

Chemical Property:

Melting Point:215 - 216 °C (ethanol)
PSA：56.21000
LogP:3.71290
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:260.106196400
Heavy Atom Count:20
Complexity:341

Purity/Quality:

97% ^*data from raw suppliers

2-PHENYL-IMIDAZO[2,1-A]PHTHALAZIN-6-YLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CN3C(=N2)C4=CC=CC=C4C(=N3)N

Technology Process of 2-Phenylimidazo[2,1-a]phthalazin-6-amine

There total 1 articles about 2-Phenylimidazo[2,1-a]phthalazin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 17987-70-1
1,4-diaminophthalazine

: 70-11-1
α-bromoacetophenone

: 54753-08-1
2-phenyl-6-aminoimidazo<2,1-a>phthalazine

Guidance literature:: In ethanol; for 4h; Heating;
DOI:10.1002/1521-4184(200201)335:1<7::AID-ARDP7>3.0.CO;2-L

Reference yield: 60.0%

: 54753-08-1
2-phenyl-6-aminoimidazo<2,1-a>phthalazine

: 449187-74-0
3-iodo-2-phenyl-imidazo[2,1-a]phthalazin-6-ylamine

Guidance literature:: With N-iodo-succinimide; In acetonitrile; at 20 ℃; for 0.75h;
DOI:10.1002/1521-4184(200201)335:1<7::AID-ARDP7>3.0.CO;2-L

Reference yield:

: 54753-08-1
2-phenyl-6-aminoimidazo<2,1-a>phthalazine

: 2,3-diphenyl-imidazo[2,1-a]phthalazin-6-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / N-iodosuccinimide / acetonitrile / 0.75 h / 20 °C

2: 48 percent / aq. NaOH / Pd(PPh₃)4 / 1,2-dimethoxy-ethane / 8 h / Heating

With sodium hydroxide; N-iodo-succinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; acetonitrile; 2: Suzuki coupling;
DOI:10.1002/1521-4184(200201)335:1<7::AID-ARDP7>3.0.CO;2-L