[1-(Benzenesulfonyl)piperidin-3-yl]methanol

Base Information

Chemical Name:[1-(Benzenesulfonyl)piperidin-3-yl]methanol
CAS No.:346691-49-4
Molecular Formula:C12H17NO3S
Molecular Weight:255.338
Hs Code.:2935009090
DSSTox Substance ID:DTXSID90409361
Mol file:346691-49-4.mol

Synonyms:346691-49-4;[1-(Phenylsulfonyl)-3-piperidinyl]methanol;[1-(benzenesulfonyl)piperidin-3-yl]methanol;(1-(Phenylsulfonyl)piperidin-3-yl)methanol;Oprea1_439804;SCHEMBL4741603;DTXSID90409361;MFCD00784283;AKOS005072407;EA-0703;CS-0332707;J-500078

Suppliers and Price of [1-(Benzenesulfonyl)piperidin-3-yl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-(Hydroxymethyl)-1-(phenylsulfonyl)piperidine
5 g
$ 720.00

SynQuest Laboratories
3-(Hydroxymethyl)-1-(phenylsulfonyl)piperidine
1 g
$ 256.00

Matrix Scientific
[1-(Phenylsulfonyl)-3-piperidinyl]methanol >95%
1g
$ 228.00

Matrix Scientific
[1-(Phenylsulfonyl)-3-piperidinyl]methanol >95%
500mg
$ 181.00

Matrix Scientific
[1-(Phenylsulfonyl)-3-piperidinyl]methanol >95%
5g
$ 524.00

Crysdot
(1-(Phenylsulfonyl)piperidin-3-yl)methanol 95+%
5g
$ 325.00

Total 2 raw suppliers

Chemical Property of [1-(Benzenesulfonyl)piperidin-3-yl]methanol

Chemical Property:

Melting Point:51～53℃
PSA：65.99000
LogP:2.09830
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:255.09291458
Heavy Atom Count:17
Complexity:330

Purity/Quality:

99% ^*data from raw suppliers

3-(Hydroxymethyl)-1-(phenylsulfonyl)piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CN(C1)S(=O)(=O)C2=CC=CC=C2)CO

Technology Process of [1-(Benzenesulfonyl)piperidin-3-yl]methanol

There total 3 articles about [1-(Benzenesulfonyl)piperidin-3-yl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.4%

: 1040877-93-7
1-benzenesulfonyl-piperidine-3-carboxylic acid methyl ester

: 346691-49-4
(1-benzenesulfonyl-piperidin-3-yl)-methanol

Guidance literature:: 1-benzenesulfonyl-piperidine-3-carboxylic acid methyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃;

With potassium hydroxide; In tetrahydrofuran; water; at 0 ℃;

Reference yield:

: 321970-54-1
1-(phenylsulfonyl)piperidine-3-carboxylic acid

: 346691-49-4
(1-benzenesulfonyl-piperidin-3-yl)-methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / 0 - 20 °C / Heating / reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

2.2: 0 °C

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran;

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 346691-49-4
(1-benzenesulfonyl-piperidin-3-yl)-methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium carbonate / water / 0.17 h / 0 °C

1.2: 0 - 20 °C

1.3: 0.25 - 0.5 h / 0 - 5 °C / pH 3

2.1: thionyl chloride / 0 - 20 °C / Heating / reflux

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

3.2: 0 °C

With lithium aluminium tetrahydride; thionyl chloride; sodium carbonate; In tetrahydrofuran; water;