3-methylenecyclobutylmethyl bromide

Base Information

• Chemical Name: 3-methylenecyclobutylmethyl bromide
• CAS No.: 10555-46-1
• Molecular Formula: C6H9Br
• Molecular Weight: 161.041
• Mol file: 10555-46-1.mol

Synonyms:3-methylenecyclobutylmethyl bromide

Chemical Property of 3-methylenecyclobutylmethyl bromide

Chemical Property:

• PSA: 0.00000
• LogP: 2.34750

Purity/Quality:

97% ^*data from raw suppliers

1-(Bromomethyl)-3-methylenecyclobutane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-methylenecyclobutylmethyl bromide

There total 5 articles about 3-methylenecyclobutylmethyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

Methanesulfonic acid 3-methylene-cyclobutylmethyl ester (110785-60-9) → 3-methylenecyclobutylmethyl bromide (10555-46-1)

Guidance literature:

With lithium bromide; In acetone; for 9h; Heating;

Reference yield:

(3-methylenecyclobutyl)methanol (10555-45-0) → 3-methylenecyclobutylmethyl bromide (10555-46-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / CH₂Cl₂ / 0.5 h / Ambient temperature

2: 48 percent / LiBr / acetone / 9 h / Heating

With triethylamine; lithium bromide; In dichloromethane; acetone;

Reference yield:

(3-methylidenecyclobutyl)methyl 4-methylbenzene-1-sulfonate → 3-methylenecyclobutylmethyl bromide (10555-46-1)

Guidance literature:

With lithium bromide; In acetone;

DOI:10.1021/ja00971a025

upstream raw materials:

Methanesulfonic acid 3-methylene-cyclobutylmethyl ester

(3-methylenecyclobutyl)methanol

3-methylenecyclobutane-1-carboxylic acid

3-methylenecyclobutanecarboxylic acid methyl ester

Downstream raw materials:

2-methyl-1,4-pentadiene

1-methyl-3-methylenecyclobutane