Methyl 3-methylenecyclobutanecarboxylate

Base Information

• Chemical Name: Methyl 3-methylenecyclobutanecarboxylate
• CAS No.: 15963-40-3
• Molecular Formula: C7H10 O2
• Molecular Weight: 126.155
• Hs Code.: 2916209090
• European Community (EC) Number: 847-873-1
• DSSTox Substance ID: DTXSID50453305
• Nikkaji Number: J1.956.978K
• Wikidata: Q82274421
• Mol file: 15963-40-3.mol

Synonyms:Methyl 3-methylenecyclobutanecarboxylate;15963-40-3;Methyl 3-methylidenecyclobutane-1-carboxylate;Cyclobutanecarboxylic acid, 3-methylene-, methyl ester;methyl 3-methylenecyclobutane-1-carboxylate;MFCD01087180;Cyclobutanecarboxylic acid, 3-methylene-, methyl ester (6CI,8CI,9CI);3-Methylenecyclobutanecarboxylic acid methyl ester;SCHEMBL9957179;DTXSID50453305;OSWTXCSCDKIANQ-UHFFFAOYSA-N;AKOS016004655;Methyl3-methylenecyclobutanecarboxylate;AM85374;PB23217;DS-15698;SY102626;CS-0046881;FT-0738499;EN300-134750;A883294

Chemical Property of Methyl 3-methylenecyclobutanecarboxylate

Chemical Property:

• Boiling Point: 56-59 °C(Press: 20 Torr)
• PSA: 26.30000
• Density: 1.01±0.1 g/cm3(Predicted)
• LogP: 1.12560
• Storage Temp.: 2-8°C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 126.068079557
• Heavy Atom Count: 9
• Complexity: 141

Purity/Quality:

97% ^*data from raw suppliers

Methyl3-Methylenecyclobutanecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1CC(=C)C1

Technology Process of Methyl 3-methylenecyclobutanecarboxylate

There total 15 articles about Methyl 3-methylenecyclobutanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-methylenecyclobutane-1-carboxylic acid (15760-36-8) + dimethyl sulfate (77-78-1) → 3-methylenecyclobutanecarboxylic acid methyl ester (15963-40-3)

Guidance literature:

With potassium carbonate; In acetone; at 25 - 70 ℃; for 12h;

Reference yield: 90.0%

3-methylenecyclobutane-1-carboxylic acid (15760-36-8) + methyl iodide (74-88-4) → 3-methylenecyclobutanecarboxylic acid methyl ester (15963-40-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 73.0%

3-methylenecyclobutane-1-carboxylic acid (15760-36-8) + diazomethyl-trimethyl-silane (18107-18-1) → 3-methylenecyclobutanecarboxylic acid methyl ester (15963-40-3)

Guidance literature:

In methanol; dichloromethane; at 0 - 20 ℃; for 0.583333h;

upstream raw materials:

1,2-propanediene

acrylic acid methyl ester

diazomethane

3-methylenecyclobutanecarbonitrile

Downstream raw materials:

spiro[2.3]hexane-5-carboxylic acid