4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

Base Information

Chemical Name:4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde
CAS No.:1460032-22-7
Molecular Formula:C₁₄H₁₁ClN₂O
Molecular Weight:258.707
Hs Code.:
Mol file:1460032-22-7.mol

Synonyms:4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

Suppliers and Price of 4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of 4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

There total 1 articles about 4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 61072-56-8
4-chloro-2-fluorobenzaldehyde

: 147739-88-6
6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

: 1460032-22-7
4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 90 ℃; Inert atmosphere;

Reference yield: 79.0%

: 1460032-22-7
4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 1460032-27-2
tert-butyl 4-[(4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]phenyl)methyl]piperazine-1-carboxylate

Guidance literature:: 4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde; 1-t-Butoxycarbonylpiperazine; In dichloromethane; at 20 ℃; for 0.5h;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃;

Reference yield:

: 1460032-22-7
4-chloro-2-[5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl]benzaldehyde

: 1460032-19-2
2,5-dioxopyrrolidin-1-yl 4-[(4-chloro-2-{5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}phenyl)methyl]piperazine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: dichloromethane / 0.5 h / 20 °C

1.2: 20 °C

2.1: trifluoroacetic acid / dichloromethane / 0 - 20 °C

3.1: triethylamine / acetonitrile / 20 °C

With triethylamine; trifluoroacetic acid; In dichloromethane; acetonitrile;