(S)-3-AMINOHEXAN-1-OL HYDROCHLORIDE

Base Information

• Chemical Name: (S)-3-AMINOHEXAN-1-OL HYDROCHLORIDE
• CAS No.: 68889-62-3
• Molecular Formula: C6H16ClNO
• Molecular Weight: 153.652
• Hs Code.: 2922199090
• Mol file: 68889-62-3.mol

Synonyms:(S)-3-AMINOHEXAN-1-OL HYDROCHLORIDE

Chemical Property of (S)-3-AMINOHEXAN-1-OL HYDROCHLORIDE

Chemical Property:

• PSA: 46.25000
• LogP: 1.99850
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(S)-3-Aminohexan-1-olhydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (S)-3-Aminohexan-1-ol hydrochloride (CAS# 68889-62-3) is used as a reagent in novel pyrimidine TLR7/8 dual agonists to treat hepatitis B.

Technology Process of (S)-3-AMINOHEXAN-1-OL HYDROCHLORIDE

There total 6 articles about (S)-3-AMINOHEXAN-1-OL HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(S)-tert-butyl (1-hydroxyhexan-3-yl)carbamate (230637-46-4) → (S)-3-aminohexan-1-ol hydrochloride (68889-62-3)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; water; at 0 - 20 ℃; for 2h;

DOI:10.1021/acs.jmedchem.6b00747

Reference yield:

(3S,αS)-tert-butyl 3-(N-benzyl-N-α-methylbenzylamino)hexanoate → (S)-3-aminohexan-1-ol hydrochloride (68889-62-3)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

2: hydrogen; palladium 10% on activated carbon / methanol / 24 h / 50 °C / 2585.81 Torr

3: triethylamine / dichloromethane / 16 h / 0 - 20 °C

4: hydrogenchloride / water; 1,4-dioxane / 2 h / 0 - 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water;

DOI:10.1021/acs.jmedchem.6b00747

Reference yield:

(S)-3-(benzyl((S)-1-phenylethyl)amino)hexan-1-ol → (S)-3-aminohexan-1-ol hydrochloride (68889-62-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen; palladium 10% on activated carbon / methanol / 24 h / 50 °C / 2585.81 Torr

2: triethylamine / dichloromethane / 16 h / 0 - 20 °C

3: hydrogenchloride / water; 1,4-dioxane / 2 h / 0 - 20 °C

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; triethylamine; In 1,4-dioxane; methanol; dichloromethane; water;

DOI:10.1021/acs.jmedchem.6b00747

upstream raw materials:

(S)-(+)-3-amino-1-hexanol

(S)-tert-butyl (1-hydroxyhexan-3-yl)carbamate

tert-butyl hex-2-enoate

Downstream raw materials:

C₁₉H₂₆N₄O₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 68889-62-3 (S)-3-AMINOHEXAN-1-OL HYDROCHLORIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send