3-NITRO-4-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER

Base Information

Chemical Name:3-NITRO-4-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER
CAS No.:947243-97-2
Molecular Formula:C17H20N4O4
Molecular Weight:0
Hs Code.:
Mol file:947243-97-2.mol

Synonyms:3-NITRO-4-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER

Suppliers and Price of 3-NITRO-4-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-NITRO-4-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER

Chemical Property:

Melting Point:206 - 210 °C
PSA：109.93000
LogP:3.69500

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 3-NITRO-4-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER

There total 2 articles about 3-NITRO-4-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 76918-64-4
ethyl 4-amino-3-nitrobenzoate

: 79074-45-6
2-(bromomethyl)-3,5,6-trimethylpyrazine

: 947243-97-2
ethyl 3-nitro-4-{[(3,5,6-trimethylpyrazin-2-yl)methyl]amino}benzoate

Guidance literature:: ethyl 4-amino-3-nitrobenzoate; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

2-(bromomethyl)-3,5,6-trimethylpyrazine; In N,N-dimethyl-formamide; for 4h; Inert atmosphere;
DOI:10.1002/cbdv.200900353

Reference yield:

: 1124-11-4
Tetramethylpyrazine

: 947243-97-2
ethyl 3-nitro-4-{[(3,5,6-trimethylpyrazin-2-yl)methyl]amino}benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 10 h / 65 °C / Irradiation

2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 20 °C

2.2: 4 h / Inert atmosphere

With N-Bromosuccinimide; sodium hydride; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide;
DOI:10.1002/cbdv.200900353

Reference yield:

: 947243-97-2
ethyl 3-nitro-4-{[(3,5,6-trimethylpyrazin-2-yl)methyl]amino}benzoate

: 947243-77-8
N-(diaminomethylidene)-3-nitro-4-{[(3,5,6-trimethylpyrazin-2-yl)methyl]amino}benzamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: isopropyl alcohol / 70 °C / Reflux

2: hydrogenchloride / ethyl acetate; isopropyl alcohol / pH 3

With hydrogenchloride; In ethyl acetate; isopropyl alcohol;
DOI:10.1002/cbdv.200900353