(3E)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one

Base Information

Chemical Name:(3E)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
CAS No.:1055412-47-9
Molecular Formula:C₁₅H₁₃ClN₂O
Molecular Weight:272.734
Hs Code.:2933990090
European Community (EC) Number:686-026-9
Mol file:1055412-47-9.mol

Synonyms:su5614;AC1NS4RE;(3E)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one;5-CHLORO-3-(3,5-DIMETHYL-1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-INDOL-2-ONE

Suppliers and Price of (3E)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
SU5614
100mg
$ 1380.00

Usbiological
SU-5614
10mg
$ 460.00

TRC
SU-5614
25mg
$ 110.00

Sigma-Aldrich
SU5614 ≥98% (HPLC)
5mg
$ 129.00

Sigma-Aldrich
SU5614 ≥98% (HPLC)
25mg
$ 486.00

Medical Isotopes, Inc.
SU-5614
100 mg
$ 2200.00

DC Chemicals
SU5614 >98%
100 mg
$ 300.00

CSNpharm
SU-5614
1g
$ 639.00

CSNpharm
SU-5614
25mg
$ 56.00

CSNpharm
SU-5614
100mg
$ 112.00

Total 23 raw suppliers

Chemical Property of (3E)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one

Chemical Property:

Boiling Point:508.6±50.0 °C(Predicted)
PKA:11.96±0.20(Predicted)
PSA：48.38000
Density:1.352±0.06 g/cm3(Predicted)
LogP:3.86270
Storage Temp.:0-6°C
Solubility.:DMSO: ≥20mg/mL
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:272.0716407
Heavy Atom Count:19
Complexity:409

Purity/Quality:

99%, ^*data from raw suppliers

SU5614 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 53

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(N1)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C
Isomeric SMILES:CC1=CC(=C(N1)/C=C/2\C3=C(C=CC(=C3)Cl)NC2=O)C
Uses SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor; selective inhibitor of VEGF and PDGF receptor tyrosine kinases.

Technology Process of (3E)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one

There total 1 articles about (3E)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%