2-Amino-4-hydroxythiophene-3-carbonitrile

Base Information

Chemical Name:2-Amino-4-hydroxythiophene-3-carbonitrile
CAS No.:99580-50-4
Molecular Formula:C5H4N2OS
Molecular Weight:140.16306
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70543494
Wikidata:Q82420395
Mol file:99580-50-4.mol

Synonyms:2-amino-4-hydroxythiophene-3-carbonitrile;99580-50-4;3-Thiophenecarbonitrile, 2-amino-4-hydroxy-;2-amino-3-cyano-4-hydroxythiophene;SCHEMBL9487040;DTXSID70543494;BBSSHLOVHLENAE-UHFFFAOYSA-N;MFCD19204858;AKOS006340745;CS-W007195;DS-14256;C77390;EN300-117834;Z1203581505

Suppliers and Price of 2-Amino-4-hydroxythiophene-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-4-hydroxythiophene-3-carbonitrile
100mg
$ 265.00

Crysdot
2-Amino-4-hydroxythiophene-3-carbonitrile 95+%
25g
$ 2376.00

Crysdot
2-Amino-4-hydroxythiophene-3-carbonitrile 95+%
10g
$ 1188.00

Crysdot
2-Amino-4-hydroxythiophene-3-carbonitrile 95+%
1g
$ 248.00

Crysdot
2-Amino-4-hydroxythiophene-3-carbonitrile 95+%
5g
$ 743.00

Biosynth Carbosynth
2-aMino-3-cyano-4-hydroxythiophene
1 g
$ 488.00

Biosynth Carbosynth
2-aMino-3-cyano-4-hydroxythiophene
500 mg
$ 280.00

Biosynth Carbosynth
2-aMino-3-cyano-4-hydroxythiophene
250 mg
$ 162.50

Biosynth Carbosynth
2-aMino-3-cyano-4-hydroxythiophene
100 mg
$ 81.00

Biosynth Carbosynth
2-aMino-3-cyano-4-hydroxythiophene
2 g
$ 849.00

Total 17 raw suppliers

Chemical Property of 2-Amino-4-hydroxythiophene-3-carbonitrile

Chemical Property:

Melting Point:>300 °C
Boiling Point:413.8±45.0 °C(Predicted)
PKA:6.93±0.15(Predicted)
PSA：98.28000
Density:1.54±0.1 g/cm3(Predicted)
LogP:1.48878
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:140.00443393
Heavy Atom Count:9
Complexity:152

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-4-hydroxythiophene-3-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(S1)N)C#N)O

Technology Process of 2-Amino-4-hydroxythiophene-3-carbonitrile

There total 4 articles about 2-Amino-4-hydroxythiophene-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1445-45-0
Trimethyl orthoacetate

: 99580-50-4
2-amino-3-cyano-4-hydroxythiophene

Guidance literature:: Trimethyl orthoacetate; With malononitrile; at 60 ℃; for 3h; Green chemistry;

With sulfur; potassium hydroxide; In water; at 60 ℃; for 0.25h; Green chemistry;
DOI:10.1080/00397911.2014.951898