2-BroMo-1-chloro-4-isopropylbenzene

Base Information

• Chemical Name: 2-BroMo-1-chloro-4-isopropylbenzene
• CAS No.: 90350-25-7
• Molecular Formula: C9H10BrCl
• Molecular Weight: 233.535
• Hs Code.: 2903999090
• Mol file: 90350-25-7.mol

Synonyms:2-BroMo-1-chloro-4-isopropylbenzene;3-Bromo-4-chloroisopropylbenzene

Chemical Property of 2-BroMo-1-chloro-4-isopropylbenzene

Chemical Property:

• PSA: 0.00000
• LogP: 4.22590
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-1-chloro-4-isopropylbenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BroMo-1-chloro-4-isopropylbenzene

There total 1 articles about 2-BroMo-1-chloro-4-isopropylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4-isopropylaniline (51605-97-1) → 2-bromo-1-chloro-4-isopropyl-benzene (90350-25-7)

Guidance literature:

With copper dichloride; isopentyl nitrite; In acetonitrile; at 65 ℃; for 1h;

Reference yield: 75.0%

2-bromo-1-chloro-4-isopropyl-benzene (90350-25-7) + 1,3,5,7,9-pentakis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) corannulene (1398052-93-1) → 1,3,5,7,9-pentakis(2-chloro-5-iso-propylphenyl)corannulene

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In tetrahydrofuran; at 95 ℃; for 48h; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.202109946

Reference yield:

2-bromo-1-chloro-4-isopropyl-benzene (90350-25-7) → (2-chloro-5-isopropylphenyl)boronic acid (875550-89-3)

Guidance literature:

2-bromo-1-chloro-4-isopropyl-benzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

With Trimethyl borate; In tetrahydrofuran; at -78 ℃; for 3.5h;

With ammonium chloride; In tetrahydrofuran; water;

upstream raw materials:

2-bromo-4-isopropylaniline

Downstream raw materials:

(2-chloro-5-isopropylphenyl)boronic acid

Refernces