N-(1-Benzhydrylazetidin-3-yl)acetamide

Base Information

Chemical Name:N-(1-Benzhydrylazetidin-3-yl)acetamide
CAS No.:102065-87-2
Molecular Formula:C₁₈H₂₀N₂O
Molecular Weight:280.37
Hs Code.:
DSSTox Substance ID:DTXSID701255651
Mol file:102065-87-2.mol

Synonyms:N-(1-Benzhydrylazetidin-3-yl)acetamide;102065-87-2;MFCD06808718;N-[1-(DIPHENYLMETHYL)AZETIDIN-3-YL]ACETAMIDE;N-[1-(Diphenylmethyl)-3-azetidinyl]-acetamide;BUTTPARK 92\50-60;SCHEMBL377735;OFNIVRIDXPYDPE-UHFFFAOYSA-N;DTXSID701255651;SB50989;PS-16613;SY321944;n-(1-benzhydryl-azetidin-3-yl)-acetamide;CS-0183541;N-[1-(Diphenylmethyl)-3-azetidinyl]acetamide;P19197

Suppliers and Price of N-(1-Benzhydrylazetidin-3-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(1-Benzhydrylazetidin-3-yl)acetamide 95+%
1g
$ 339.00

Chemenu
N-(1-benzhydrylazetidin-3-yl)acetamide 95%
1g
$ 320.00

Alichem
N-(1-Benzhydrylazetidin-3-yl)acetamide
1g
$ 281.52

Acrotein
N-[1-(Diphenylmethyl)-3-azetidinyl]-acetamide 97%
1g
$ 366.67

Total 9 raw suppliers

Chemical Property of N-(1-Benzhydrylazetidin-3-yl)acetamide

Chemical Property:

Melting Point:150-160 °C
Boiling Point:449.5±34.0 °C(Predicted)
PKA:15.52±0.20(Predicted)
PSA：32.34000
Density:1.15±0.1 g/cm3(Predicted)
LogP:2.92510
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:280.157563266
Heavy Atom Count:21
Complexity:321

Purity/Quality:

99%, ^*data from raw suppliers

N-(1-Benzhydrylazetidin-3-yl)acetamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1CN(C1)C(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of N-(1-Benzhydrylazetidin-3-yl)acetamide

There total 4 articles about N-(1-Benzhydrylazetidin-3-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 108-24-7
acetic anhydride

: 40432-52-8
1-benzhydrylazetidin-3-ylamine

: 102065-87-2
N-(1-benzhydryl-azetidin-3-yl)-acetamide

Guidance literature:: In ethyl acetate; for 1.5h; Ambient temperature;
DOI:10.1002/jhet.5570220405

Reference yield:

: 40432-52-8
1-benzhydrylazetidin-3-ylamine

: 75-36-5
acetyl chloride

: 102065-87-2
N-(1-benzhydryl-azetidin-3-yl)-acetamide

Guidance literature:

Reference yield:

: 33301-41-6
1-benzhydryl-3-azetidinyl methanesulfonate

: 102065-87-2
N-(1-benzhydryl-azetidin-3-yl)-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / de bromure d'hexadecyl-tributyl phosphonium / toluene / 5 h / Heating

2: 96 percent / 85percent N₂H₄ / methanol / 2 h / Heating

3: 82 percent / ethyl acetate / 1.5 h / Ambient temperature

With de bromure d'hexadecyl-tributyl phosphonium; hydrazine hydrate; In methanol; ethyl acetate; toluene;
DOI:10.1002/jhet.5570220405